Sensitive detection of Aβ protofibrils by proximity ligation - relevance for Alzheimer's disease
<p>Abstract</p> <p>Background</p> <p>Protein aggregation plays important roles in several neurodegenerative disorders. For instance, insoluble aggregates of phosphorylated tau and of Aβ peptides are cornerstones in the pathology of Alzheimer's disease. Soluble prot...
Main Authors: | , , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2010-10-01
|
Series: | BMC Neuroscience |
Online Access: | http://www.biomedcentral.com/1471-2202/11/124 |