Unc13A and Unc13B contribute to the decoding of distinct sensory information in Drosophila

The physical distance between synaptic Ca2+ channels and sensors modulates short-term plasticity (STP). Here, the authors show that synaptic release factors Unc13A and Unc13B distinctly couple with Ca2+ channels and contribute to the neural decoding of distinct sensory information in Drosophila.

Bibliographic Details
Main Authors:	Atefeh Pooryasin, Marta Maglione, Marco Schubert, Tanja Matkovic-Rachid, Sayed-mohammad Hasheminasab, Ulrike Pech, André Fiala, Thorsten Mielke, Stephan J. Sigrist
Format:	Article
Language:	English
Published:	Nature Publishing Group 2021-03-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-021-22180-6

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spelling	doaj-1555961b6bb840d7b6165c99930a8b082021-03-28T11:12:31ZengNature Publishing GroupNature Communications2041-17232021-03-0112111410.1038/s41467-021-22180-6Unc13A and Unc13B contribute to the decoding of distinct sensory information in DrosophilaAtefeh Pooryasin0Marta Maglione1Marco Schubert2Tanja Matkovic-Rachid3Sayed-mohammad Hasheminasab4Ulrike Pech5André Fiala6Thorsten Mielke7Stephan J. Sigrist8Institute for Biology/Genetics, Freie Universität BerlinInstitute for Biology/Genetics, Freie Universität BerlinInstitute for Biology/Genetics, Freie Universität BerlinInstitute for Biology/Genetics, Freie Universität BerlinDepartment of Dermatology, Venereology and Allergology, Charité UniversitätsmedizinDepartment of Molecular Neurobiology of Behavior, Johann-Friedrich-Blumenbach-Institute for Zoology and Anthropology, University of GöttingenDepartment of Molecular Neurobiology of Behavior, Johann-Friedrich-Blumenbach-Institute for Zoology and Anthropology, University of GöttingenMax Planck Institute for Molecular Genetics, Berlin, Microscopy and Cryo-Electron Microscopy GroupInstitute for Biology/Genetics, Freie Universität BerlinThe physical distance between synaptic Ca2+ channels and sensors modulates short-term plasticity (STP). Here, the authors show that synaptic release factors Unc13A and Unc13B distinctly couple with Ca2+ channels and contribute to the neural decoding of distinct sensory information in Drosophila.https://doi.org/10.1038/s41467-021-22180-6
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Atefeh Pooryasin Marta Maglione Marco Schubert Tanja Matkovic-Rachid Sayed-mohammad Hasheminasab Ulrike Pech André Fiala Thorsten Mielke Stephan J. Sigrist
spellingShingle	Atefeh Pooryasin Marta Maglione Marco Schubert Tanja Matkovic-Rachid Sayed-mohammad Hasheminasab Ulrike Pech André Fiala Thorsten Mielke Stephan J. Sigrist Unc13A and Unc13B contribute to the decoding of distinct sensory information in Drosophila Nature Communications
author_facet	Atefeh Pooryasin Marta Maglione Marco Schubert Tanja Matkovic-Rachid Sayed-mohammad Hasheminasab Ulrike Pech André Fiala Thorsten Mielke Stephan J. Sigrist
author_sort	Atefeh Pooryasin
title	Unc13A and Unc13B contribute to the decoding of distinct sensory information in Drosophila
title_short	Unc13A and Unc13B contribute to the decoding of distinct sensory information in Drosophila
title_full	Unc13A and Unc13B contribute to the decoding of distinct sensory information in Drosophila
title_fullStr	Unc13A and Unc13B contribute to the decoding of distinct sensory information in Drosophila
title_full_unstemmed	Unc13A and Unc13B contribute to the decoding of distinct sensory information in Drosophila
title_sort	unc13a and unc13b contribute to the decoding of distinct sensory information in drosophila
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2021-03-01
description	The physical distance between synaptic Ca2+ channels and sensors modulates short-term plasticity (STP). Here, the authors show that synaptic release factors Unc13A and Unc13B distinctly couple with Ca2+ channels and contribute to the neural decoding of distinct sensory information in Drosophila.
url	https://doi.org/10.1038/s41467-021-22180-6
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Unc13A and Unc13B contribute to the decoding of distinct sensory information in Drosophila

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