Description and Characterization of a Novel Human Mast Cell Line for Scientific Study

Description and Characterization of a Novel Human Mast Cell Line for Scientific Study

Background: Laboratory of allergic diseases 2 (LAD2) human mast cells were developed over 15 years ago and have been distributed worldwide for studying mast cell proliferation, receptor expression, mediator release/inhibition, and signaling. LAD2 cells were derived from CD34+ cells following marrow...

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Bibliographic Details
Main Authors: Arnold S. Kirshenbaum, Yuzhi Yin, J. Bruce Sundstrom, Geethani Bandara, Dean D. Metcalfe
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:International Journal of Molecular Sciences
Subjects:
mast cell
lad cells
hiv
allergy
fcεr1
stem cell factor
c-<i>kit</i>
socs
<i>myc</i>
Online Access:https://www.mdpi.com/1422-0067/20/22/5520

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