DSTYK Promotes Metastasis and Chemoresistance via EMT in Colorectal Cancer

DSTYK Promotes Metastasis and Chemoresistance via EMT in Colorectal Cancer

ObjectiveTumor metastasis and resistance to chemotherapy are two critical factors that contribute to the high death rate of colorectal cancer (CRC) patients. Metastasis is facilitated by the epithelial-mesenchymal transition (EMT) of tumor cells, which has emerged not only as a fundamental process d...

Full description

Bibliographic Details
Main Authors: Jinyu Zhang, Zachary Miller, Phillip R. Musich, Ashlin E. Thomas, Zhi Q. Yao, Qian Xie, Philip H. Howe, Yong Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Pharmacology
Subjects:
dual serine/threonine and tyrosine protein kinase
colorectal cancer
epithelial-mesenchymal transition
transforming growth factor-β
chemoresistance
metastasis
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.01250/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.01250/full

Similar Items