New tools to study DNA double-strand break repair pathway choice.
A broken DNA molecule is difficult to repair, highly mutagenic, and extremely cytotoxic. Such breaks can be repaired by homology-independent or homology-directed mechanisms. Little is known about the network that controls the repair pathway choice except that a licensing step for homology-mediated r...
Main Authors: | Daniel Gomez-Cabello, Sonia Jimeno, María Jesús Fernández-Ávila, Pablo Huertas |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3796453?pdf=render |
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