Knockdown of CYP24A1 Aggravates 1α,25(OH)2D3-Inhibited Migration and Invasion of Mouse Ovarian Epithelial Cells by Suppressing EMT

Knockdown of CYP24A1 Aggravates 1α,25(OH)2D3-Inhibited Migration and Invasion of Mouse Ovarian Epithelial Cells by Suppressing EMT

Epithelial-mesenchymal transition (EMT) bestows cancer cells with motile and invasive properties. But for ovarian tissues, EMT plays a physiological role in the postovulatory repair of ovary surface epithelial (OSE) cells. Accumulating data indicated that 1α,25(OH)2D3 decreased both the migration an...

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Bibliographic Details
Main Authors: Ping Wang, Jiming Xu, Weijing You, Yongfeng Hou, Shuiliang Wang, Yujie Ma, Jianming Tan, Zengli Zhang, Wentao Hu, Bingyan Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Oncology
Subjects:
CYP24A1
1α,25(OH)2D3
migration
invasion
epithelial–mesenchymal transition
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01258/full

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https://www.frontiersin.org/article/10.3389/fonc.2020.01258/full

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