CFP1 Regulates Histone H3K4 Trimethylation and Developmental Potential in Mouse Oocytes

CFP1 Regulates Histone H3K4 Trimethylation and Developmental Potential in Mouse Oocytes

Summary: Trimethylation of histone H3 at lysine-4 (H3K4me3) is associated with eukaryotic gene promoters and poises their transcriptional activation during development. To examine the in vivo function of H3K4me3 in the absence of DNA replication, we deleted CXXC finger protein 1 (CFP1), the DNA-bind...

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Bibliographic Details
Main Authors:	Chao Yu, Xiaoying Fan, Qian-Qian Sha, Hui-Han Wang, Bo-Tai Li, Xing-Xing Dai, Li Shen, Junping Liu, Lie Wang, Kui Liu, Fuchou Tang, Heng-Yu Fan
Format:	Article
Language:	English
Published:	Elsevier 2017-08-01
Series:	Cell Reports
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124717309646

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