Predicting Dimensions in Microfluidic Paper Based Analytical Devices
The main problem for the expansion of the use of microfluidic paper-based analytical devices and, thus, their mass production is their inherent lack of fluid flow control due to its uncontrolled fabrication protocols. To address this issue, the first step is the generation of uniform and reliable mi...
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doaj-1584cfba849b4bf08ce041f6ddfaffc22020-12-27T00:00:12ZengMDPI AGSensors1424-82202021-12-012110110110.3390/s21010101Predicting Dimensions in Microfluidic Paper Based Analytical DevicesRaquel Catalan-Carrio0Tugçe Akyazi1Lourdes Basabe-Desmonts2Fernando Benito-Lopez3Microfluidics Cluster UPV/EHU, Analytical Microsystems & Materials for Lab-on-a-Chip (AMMa-LOAC) Group, Analytical Chemistry Department, University of the Basque Country UPV/EHU, 01006 Vitoria-Gasteiz, SpainMicrofluidics Cluster UPV/EHU, Analytical Microsystems & Materials for Lab-on-a-Chip (AMMa-LOAC) Group, Analytical Chemistry Department, University of the Basque Country UPV/EHU, 01006 Vitoria-Gasteiz, SpainMicrofluidics Cluster UPV/EHU, BIOMICs Microfluidics Group, Lascaray Research Center, University of the Basque Country UPV/EHU, 01006 Vitoria-Gasteiz, SpainMicrofluidics Cluster UPV/EHU, Analytical Microsystems & Materials for Lab-on-a-Chip (AMMa-LOAC) Group, Analytical Chemistry Department, University of the Basque Country UPV/EHU, 01006 Vitoria-Gasteiz, SpainThe main problem for the expansion of the use of microfluidic paper-based analytical devices and, thus, their mass production is their inherent lack of fluid flow control due to its uncontrolled fabrication protocols. To address this issue, the first step is the generation of uniform and reliable microfluidic channels. The most common paper microfluidic fabrication method is wax printing, which consists of two parts, printing and heating, where heating is a critical step for the fabrication of reproducible device dimensions. In order to bring paper-based devices to success, it is essential to optimize the fabrication process in order to always get a reproducible device. Therefore, the optimization of the heating process and the analysis of the parameters that could affect the final dimensions of the device, such as its shape, the width of the wax barrier and the internal area of the device, were performed. Moreover, we present a method to predict reproducible devices with controlled working areas in a simple manner.https://www.mdpi.com/1424-8220/21/1/101LOCwax printingpaper microfluidicsµPADpaper microfluidics fabrication |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Raquel Catalan-Carrio Tugçe Akyazi Lourdes Basabe-Desmonts Fernando Benito-Lopez |
spellingShingle |
Raquel Catalan-Carrio Tugçe Akyazi Lourdes Basabe-Desmonts Fernando Benito-Lopez Predicting Dimensions in Microfluidic Paper Based Analytical Devices Sensors LOC wax printing paper microfluidics µPAD paper microfluidics fabrication |
author_facet |
Raquel Catalan-Carrio Tugçe Akyazi Lourdes Basabe-Desmonts Fernando Benito-Lopez |
author_sort |
Raquel Catalan-Carrio |
title |
Predicting Dimensions in Microfluidic Paper Based Analytical Devices |
title_short |
Predicting Dimensions in Microfluidic Paper Based Analytical Devices |
title_full |
Predicting Dimensions in Microfluidic Paper Based Analytical Devices |
title_fullStr |
Predicting Dimensions in Microfluidic Paper Based Analytical Devices |
title_full_unstemmed |
Predicting Dimensions in Microfluidic Paper Based Analytical Devices |
title_sort |
predicting dimensions in microfluidic paper based analytical devices |
publisher |
MDPI AG |
series |
Sensors |
issn |
1424-8220 |
publishDate |
2021-12-01 |
description |
The main problem for the expansion of the use of microfluidic paper-based analytical devices and, thus, their mass production is their inherent lack of fluid flow control due to its uncontrolled fabrication protocols. To address this issue, the first step is the generation of uniform and reliable microfluidic channels. The most common paper microfluidic fabrication method is wax printing, which consists of two parts, printing and heating, where heating is a critical step for the fabrication of reproducible device dimensions. In order to bring paper-based devices to success, it is essential to optimize the fabrication process in order to always get a reproducible device. Therefore, the optimization of the heating process and the analysis of the parameters that could affect the final dimensions of the device, such as its shape, the width of the wax barrier and the internal area of the device, were performed. Moreover, we present a method to predict reproducible devices with controlled working areas in a simple manner. |
topic |
LOC wax printing paper microfluidics µPAD paper microfluidics fabrication |
url |
https://www.mdpi.com/1424-8220/21/1/101 |
work_keys_str_mv |
AT raquelcatalancarrio predictingdimensionsinmicrofluidicpaperbasedanalyticaldevices AT tugceakyazi predictingdimensionsinmicrofluidicpaperbasedanalyticaldevices AT lourdesbasabedesmonts predictingdimensionsinmicrofluidicpaperbasedanalyticaldevices AT fernandobenitolopez predictingdimensionsinmicrofluidicpaperbasedanalyticaldevices |
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