Lack of PD-L1 expression by iNKT cells improves the course of influenza A infection.

Lack of PD-L1 expression by iNKT cells improves the course of influenza A infection.

There is evidence indicating that invariant Natural Killer T (iNKT) cells play an important role in defense against influenza A virus (IAV). However, the effect of inhibitory receptor, programmed death-1 (PD-1), and its ligands, programmed death ligand (PD-L) 1 and 2 on iNKT cells in protection agai...

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Bibliographic Details
Main Authors: Hadi Maazi, Abinav K Singh, Anneliese O Speak, Vincent Lombardi, Jonathan Lam, Bryant Khoo, Kyung Soo Inn, Arlene H Sharpe, Jae U Jung, Omid Akbari
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3598698?pdf=render

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