Impact of iterative model reconstruction combined with dose reduction on the image quality of head and neck CTA in children
Abstract This study aimed to evaluate the imaging quality of head and neck computed tomographic angiography (CTA) in pediatric patients at a lowered radiation dose by combining an iterative model reconstruction (IMR) with low voltage scanning. Eighty-three pediatric patients were randomized into two...
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2018-08-01
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doaj-15b724526dd44a92b93c421e21c31d802020-12-08T05:01:11ZengNature Publishing GroupScientific Reports2045-23222018-08-01811810.1038/s41598-018-30300-4Impact of iterative model reconstruction combined with dose reduction on the image quality of head and neck CTA in childrenBochao Cheng0Haoyang Xing1Du Lei2Yingkun Guo3Gang Ning4Qiyong Gong5Wu Cai6Department of Radiology, West China Second University Hospital, Sichuan UniversityHuaxi MR Research Center, Department of Radiology, West China Hospital of Sichuan UniversityDepartment of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King’s College LondonDepartment of Radiology, West China Second University Hospital, Sichuan UniversityDepartment of Radiology, West China Second University Hospital, Sichuan UniversityHuaxi MR Research Center, Department of Radiology, West China Hospital of Sichuan UniversityDepartment of Radiology, Second Affiliated Hospital of Soochow UniversityAbstract This study aimed to evaluate the imaging quality of head and neck computed tomographic angiography (CTA) in pediatric patients at a lowered radiation dose by combining an iterative model reconstruction (IMR) with low voltage scanning. Eighty-three pediatric patients were randomized into two groups as follows: Group A (n = 42), 100 kV/50 ml contrast media (CM), using filtered back projection (FBP); and Group B (n = 41), 80 kV/30 ml CM, using IMR. The enhanced CT value of the arteries, the image noise, the signal-to-noise ratio (SNR)/contrast-to-noise ratio (CNR), the image quality, the effective radiation dose (ED) and the iodine intake were compared between the two groups. The mean ED and iodine intake of group B were reduced by 69.8% and 40.0%, respectively, compared to those of group A. The mean CT values of the arteries in group B were higher than those in group A (p < 0.01), whereas the image noise of group B was lower than that of group A (p < 0.01). Group B exhibited a better image quality and a higher mean CNR/SNR than that of group A (p < 0.01). Compared to FBP, IMR in head and neck CTA enables a significant reduction in the radiation dose while preserving the diagnostic image quality. Thus, IMR, combined with low tube voltage scanning, provided an excellent solution for improving the image quality of craniocervical vessels in children.https://doi.org/10.1038/s41598-018-30300-4 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Bochao Cheng Haoyang Xing Du Lei Yingkun Guo Gang Ning Qiyong Gong Wu Cai |
spellingShingle |
Bochao Cheng Haoyang Xing Du Lei Yingkun Guo Gang Ning Qiyong Gong Wu Cai Impact of iterative model reconstruction combined with dose reduction on the image quality of head and neck CTA in children Scientific Reports |
author_facet |
Bochao Cheng Haoyang Xing Du Lei Yingkun Guo Gang Ning Qiyong Gong Wu Cai |
author_sort |
Bochao Cheng |
title |
Impact of iterative model reconstruction combined with dose reduction on the image quality of head and neck CTA in children |
title_short |
Impact of iterative model reconstruction combined with dose reduction on the image quality of head and neck CTA in children |
title_full |
Impact of iterative model reconstruction combined with dose reduction on the image quality of head and neck CTA in children |
title_fullStr |
Impact of iterative model reconstruction combined with dose reduction on the image quality of head and neck CTA in children |
title_full_unstemmed |
Impact of iterative model reconstruction combined with dose reduction on the image quality of head and neck CTA in children |
title_sort |
impact of iterative model reconstruction combined with dose reduction on the image quality of head and neck cta in children |
publisher |
Nature Publishing Group |
series |
Scientific Reports |
issn |
2045-2322 |
publishDate |
2018-08-01 |
description |
Abstract This study aimed to evaluate the imaging quality of head and neck computed tomographic angiography (CTA) in pediatric patients at a lowered radiation dose by combining an iterative model reconstruction (IMR) with low voltage scanning. Eighty-three pediatric patients were randomized into two groups as follows: Group A (n = 42), 100 kV/50 ml contrast media (CM), using filtered back projection (FBP); and Group B (n = 41), 80 kV/30 ml CM, using IMR. The enhanced CT value of the arteries, the image noise, the signal-to-noise ratio (SNR)/contrast-to-noise ratio (CNR), the image quality, the effective radiation dose (ED) and the iodine intake were compared between the two groups. The mean ED and iodine intake of group B were reduced by 69.8% and 40.0%, respectively, compared to those of group A. The mean CT values of the arteries in group B were higher than those in group A (p < 0.01), whereas the image noise of group B was lower than that of group A (p < 0.01). Group B exhibited a better image quality and a higher mean CNR/SNR than that of group A (p < 0.01). Compared to FBP, IMR in head and neck CTA enables a significant reduction in the radiation dose while preserving the diagnostic image quality. Thus, IMR, combined with low tube voltage scanning, provided an excellent solution for improving the image quality of craniocervical vessels in children. |
url |
https://doi.org/10.1038/s41598-018-30300-4 |
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