ABHD17 proteins are novel protein depalmitoylases that regulate N-Ras palmitate turnover and subcellular localization
Dynamic changes in protein S-palmitoylation are critical for regulating protein localization and signaling. Only two enzymes - the acyl-protein thioesterases APT1 and APT2 – are known to catalyze palmitate removal from cytosolic cysteine residues. It is unclear if these enzymes act constitutively on...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2015-12-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/11306 |