Cutaneous and Labyrinthine Tolerance of Bioactive Glass S53P4 in Mastoid and Epitympanic Obliteration Surgery: Prospective Clinical Study
Objective. To evaluate the cutaneous and the inner ear tolerance of bioactive glass S53P4 when used in the mastoid and epitympanic obliteration for chronic otitis surgery. Material and Methods. Forty-one cases have been included in this prospective study. Cutaneous tolerance was clinically evaluated...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2015-01-01
|
Series: | BioMed Research International |
Online Access: | http://dx.doi.org/10.1155/2015/242319 |
id |
doaj-15d6451600f048bfa2c523aa3f78f6ed |
---|---|
record_format |
Article |
spelling |
doaj-15d6451600f048bfa2c523aa3f78f6ed2020-11-24T20:58:02ZengHindawi LimitedBioMed Research International2314-61332314-61412015-01-01201510.1155/2015/242319242319Cutaneous and Labyrinthine Tolerance of Bioactive Glass S53P4 in Mastoid and Epitympanic Obliteration Surgery: Prospective Clinical StudyDaniele Bernardeschi0Yann Nguyen1Francesca Yoshie Russo2Isabelle Mosnier3Evelyne Ferrary4Olivier Sterkers5AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Service d’Oto-Rhino-Laryngologie, Département d’Otologie, Implants Auditifs et Chirurgie de Base du Crâne, 75013 Paris, FranceAP-HP, Groupe Hospitalier Pitié-Salpêtrière, Service d’Oto-Rhino-Laryngologie, Département d’Otologie, Implants Auditifs et Chirurgie de Base du Crâne, 75013 Paris, FranceAP-HP, Groupe Hospitalier Pitié-Salpêtrière, Service d’Oto-Rhino-Laryngologie, Département d’Otologie, Implants Auditifs et Chirurgie de Base du Crâne, 75013 Paris, FranceAP-HP, Groupe Hospitalier Pitié-Salpêtrière, Service d’Oto-Rhino-Laryngologie, Département d’Otologie, Implants Auditifs et Chirurgie de Base du Crâne, 75013 Paris, FranceAP-HP, Groupe Hospitalier Pitié-Salpêtrière, Service d’Oto-Rhino-Laryngologie, Département d’Otologie, Implants Auditifs et Chirurgie de Base du Crâne, 75013 Paris, FranceAP-HP, Groupe Hospitalier Pitié-Salpêtrière, Service d’Oto-Rhino-Laryngologie, Département d’Otologie, Implants Auditifs et Chirurgie de Base du Crâne, 75013 Paris, FranceObjective. To evaluate the cutaneous and the inner ear tolerance of bioactive glass S53P4 when used in the mastoid and epitympanic obliteration for chronic otitis surgery. Material and Methods. Forty-one cases have been included in this prospective study. Cutaneous tolerance was clinically evaluated 1 week, 1 month, and 3 months after surgery with a physical examination of the retroauricular and external auditory canal (EAC) skin and the presence of otalgia; the inner ear tolerance was assessed by bone-conduction hearing threshold 1 day after surgery and by the presence of vertigo or imbalance. Results. All surgeries but 1 were uneventful: all patients maintained the preoperative bone-conduction hearing threshold except for one case in which the round window membrane was opened during the dissection of the cholesteatoma in the hypotympanum and this led to a dead ear. No dizziness or vertigo was reported. Three months after surgery, healing was achieved in all cases with a healthy painless skin. No cases of revision surgery for removal of the granules occurred in this study. Conclusion. The bioactive glass S53P4 is a well-tolerated biomaterial for primary or revision chronic otitis surgery, as shown by the local skin reaction which lasted less than 3 months and by the absence of labyrinthine complications.http://dx.doi.org/10.1155/2015/242319 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Daniele Bernardeschi Yann Nguyen Francesca Yoshie Russo Isabelle Mosnier Evelyne Ferrary Olivier Sterkers |
spellingShingle |
Daniele Bernardeschi Yann Nguyen Francesca Yoshie Russo Isabelle Mosnier Evelyne Ferrary Olivier Sterkers Cutaneous and Labyrinthine Tolerance of Bioactive Glass S53P4 in Mastoid and Epitympanic Obliteration Surgery: Prospective Clinical Study BioMed Research International |
author_facet |
Daniele Bernardeschi Yann Nguyen Francesca Yoshie Russo Isabelle Mosnier Evelyne Ferrary Olivier Sterkers |
author_sort |
Daniele Bernardeschi |
title |
Cutaneous and Labyrinthine Tolerance of Bioactive Glass S53P4 in Mastoid and Epitympanic Obliteration Surgery: Prospective Clinical Study |
title_short |
Cutaneous and Labyrinthine Tolerance of Bioactive Glass S53P4 in Mastoid and Epitympanic Obliteration Surgery: Prospective Clinical Study |
title_full |
Cutaneous and Labyrinthine Tolerance of Bioactive Glass S53P4 in Mastoid and Epitympanic Obliteration Surgery: Prospective Clinical Study |
title_fullStr |
Cutaneous and Labyrinthine Tolerance of Bioactive Glass S53P4 in Mastoid and Epitympanic Obliteration Surgery: Prospective Clinical Study |
title_full_unstemmed |
Cutaneous and Labyrinthine Tolerance of Bioactive Glass S53P4 in Mastoid and Epitympanic Obliteration Surgery: Prospective Clinical Study |
title_sort |
cutaneous and labyrinthine tolerance of bioactive glass s53p4 in mastoid and epitympanic obliteration surgery: prospective clinical study |
publisher |
Hindawi Limited |
series |
BioMed Research International |
issn |
2314-6133 2314-6141 |
publishDate |
2015-01-01 |
description |
Objective. To evaluate the cutaneous and the inner ear tolerance of bioactive glass S53P4 when used in the mastoid and epitympanic obliteration for chronic otitis surgery. Material and Methods. Forty-one cases have been included in this prospective study. Cutaneous tolerance was clinically evaluated 1 week, 1 month, and 3 months after surgery with a physical examination of the retroauricular and external auditory canal (EAC) skin and the presence of otalgia; the inner ear tolerance was assessed by bone-conduction hearing threshold 1 day after surgery and by the presence of vertigo or imbalance. Results. All surgeries but 1 were uneventful: all patients maintained the preoperative bone-conduction hearing threshold except for one case in which the round window membrane was opened during the dissection of the cholesteatoma in the hypotympanum and this led to a dead ear. No dizziness or vertigo was reported. Three months after surgery, healing was achieved in all cases with a healthy painless skin. No cases of revision surgery for removal of the granules occurred in this study. Conclusion. The bioactive glass S53P4 is a well-tolerated biomaterial for primary or revision chronic otitis surgery, as shown by the local skin reaction which lasted less than 3 months and by the absence of labyrinthine complications. |
url |
http://dx.doi.org/10.1155/2015/242319 |
work_keys_str_mv |
AT danielebernardeschi cutaneousandlabyrinthinetoleranceofbioactiveglasss53p4inmastoidandepitympanicobliterationsurgeryprospectiveclinicalstudy AT yannnguyen cutaneousandlabyrinthinetoleranceofbioactiveglasss53p4inmastoidandepitympanicobliterationsurgeryprospectiveclinicalstudy AT francescayoshierusso cutaneousandlabyrinthinetoleranceofbioactiveglasss53p4inmastoidandepitympanicobliterationsurgeryprospectiveclinicalstudy AT isabellemosnier cutaneousandlabyrinthinetoleranceofbioactiveglasss53p4inmastoidandepitympanicobliterationsurgeryprospectiveclinicalstudy AT evelyneferrary cutaneousandlabyrinthinetoleranceofbioactiveglasss53p4inmastoidandepitympanicobliterationsurgeryprospectiveclinicalstudy AT oliviersterkers cutaneousandlabyrinthinetoleranceofbioactiveglasss53p4inmastoidandepitympanicobliterationsurgeryprospectiveclinicalstudy |
_version_ |
1716786661836193792 |