Cytoneme delivery of Sonic Hedgehog from ligand-producing cells requires Myosin 10 and a Dispatched-BOC/CDON co-receptor complex
Morphogens function in concentration-dependent manners to instruct cell fate during tissue patterning. The cytoneme morphogen transport model posits that specialized filopodia extend between morphogen-sending and responding cells to ensure that appropriate signaling thresholds are achieved. How morp...
Main Authors: | Eric T Hall, Miriam E Dillard, Daniel P Stewart, Yan Zhang, Ben Wagner, Rachel M Levine, Shondra M Pruett-Miller, April Sykes, Jamshid Temirov, Richard E Cheney, Motomi Mori, Camenzind G Robinson, Stacey K Ogden |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2021-02-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/61432 |
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