Effect of bosentan therapy in persistent pulmonary hypertension of the newborn

Effect of bosentan therapy in persistent pulmonary hypertension of the newborn

Background: Persistent pulmonary hypertension of the newborn (PPHN) contributes to neonatal hypoxemia and is associated with a high mortality. Some PPHN patients are unresponsive to inhaled nitric oxide (iNO). Bosentan, an oral endothelin-1 receptor antagonist, reduces pulmonary vascular resistance...

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Bibliographic Details
Main Authors: Gunlawadee Maneenil, Anucha Thatrimontrichai, Waricha Janjindamai, Supaporn Dissaneevate
Format: Article
Language:English
Published: Elsevier 2018-02-01
Series:Pediatrics and Neonatology
Subjects:
bosentan
newborn
persistent pulmonary hypertension
Online Access:http://www.sciencedirect.com/science/article/pii/S1875957217304102

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