Prevalence of Leukemia and Associated Factors among Patients with Abnormal Hematological Parameters in Jimma Medical Center, Southwest Ethiopia: A Cross-Sectional Study
Introduction. Leukemia is a heterogeneous group of hematological disorder which comprise several diverse and biologically distinct subgroups. Leukemia represents the 11th and 10th most frequent cause of cancer morbidity and mortality worldwide, respectively. Adequate data regarding the prevalence of...
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doaj-1600b423a71d49468cad4ea6cb933cef2021-07-02T18:34:10ZengHindawi LimitedAdvances in Hematology1687-91041687-91122020-01-01202010.1155/2020/20141522014152Prevalence of Leukemia and Associated Factors among Patients with Abnormal Hematological Parameters in Jimma Medical Center, Southwest Ethiopia: A Cross-Sectional StudyWoldeteklehaymanot Kassahun0Girum Tesfaye1Lealem Gedefaw Bimerew2Diriba Fufa3Wondimagen Adissu4Tilahun Yemane5Department of Medical Laboratory Sciences, College of Medicine and Health Sciences, Arbaminch University, Arbaminch, EthiopiaSchool of Medical Laboratory Sciences, Faculty of Health Sciences, Institute of Health, Jimma University, Jimma, EthiopiaSchool of Medical Laboratory Sciences, Faculty of Health Sciences, Institute of Health, Jimma University, Jimma, EthiopiaDepartment of Pediatrics, Faculty of Medical Science, Institute of Health, Jimma University, Jimma Medical Center, Jimma, EthiopiaSchool of Medical Laboratory Sciences, Faculty of Health Sciences, Institute of Health, Jimma University, Jimma, EthiopiaSchool of Medical Laboratory Sciences, Faculty of Health Sciences, Institute of Health, Jimma University, Jimma, EthiopiaIntroduction. Leukemia is a heterogeneous group of hematological disorder which comprise several diverse and biologically distinct subgroups. Leukemia represents the 11th and 10th most frequent cause of cancer morbidity and mortality worldwide, respectively. Adequate data regarding the prevalence of leukemia are lacking in Ethiopia, particularly in the study area. This study is aimed to determine the prevalence of leukemia and associated factors among patients who have abnormal hematological parameters in Jimma Medical Center. Methodology. A facility-based cross-sectional study was conducted involving 332 patients who have abnormal hematological parameters. Complete blood count from venous blood was made with Sysmex autohematology analyzer (Sysmex XS-500i and XT-1800; Kobe, Japan). Peripheral blood morphology and bone marrow aspirate examination were done for each patient. Descriptive statistics for the prevalence of leukemia and multinomial logistic regression analysis to assess associated factors were executed with IBM SPSS version 25. Results. The prevalence of leukemia was 9.3%, while acute myeloid leukemia, Acute Lymphoid Leukemia, Chronic Myeloid Leukemia, Chronic Lymphoid Leukemia, Myelodysplastic Syndrome, and undifferentiated leukemia comprises 3.6%, 2.7%, 1.8%, 0.6%, and 0.3%, respectively. Older Age (p=0.019), being male (p=0.047), being anemic (p=0.03), and rural residency of a patient (p=0.044) were significantly associated with having acute myeloid leukemia. Conclusion. The prevalence of leukemia among patients who have abnormal hematological parameters in Jimma Medical Center is significant which needs further comprehensive investigations of the associated factors and predictors with more up to date diagnostic methods.http://dx.doi.org/10.1155/2020/2014152 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Woldeteklehaymanot Kassahun Girum Tesfaye Lealem Gedefaw Bimerew Diriba Fufa Wondimagen Adissu Tilahun Yemane |
spellingShingle |
Woldeteklehaymanot Kassahun Girum Tesfaye Lealem Gedefaw Bimerew Diriba Fufa Wondimagen Adissu Tilahun Yemane Prevalence of Leukemia and Associated Factors among Patients with Abnormal Hematological Parameters in Jimma Medical Center, Southwest Ethiopia: A Cross-Sectional Study Advances in Hematology |
author_facet |
Woldeteklehaymanot Kassahun Girum Tesfaye Lealem Gedefaw Bimerew Diriba Fufa Wondimagen Adissu Tilahun Yemane |
author_sort |
Woldeteklehaymanot Kassahun |
title |
Prevalence of Leukemia and Associated Factors among Patients with Abnormal Hematological Parameters in Jimma Medical Center, Southwest Ethiopia: A Cross-Sectional Study |
title_short |
Prevalence of Leukemia and Associated Factors among Patients with Abnormal Hematological Parameters in Jimma Medical Center, Southwest Ethiopia: A Cross-Sectional Study |
title_full |
Prevalence of Leukemia and Associated Factors among Patients with Abnormal Hematological Parameters in Jimma Medical Center, Southwest Ethiopia: A Cross-Sectional Study |
title_fullStr |
Prevalence of Leukemia and Associated Factors among Patients with Abnormal Hematological Parameters in Jimma Medical Center, Southwest Ethiopia: A Cross-Sectional Study |
title_full_unstemmed |
Prevalence of Leukemia and Associated Factors among Patients with Abnormal Hematological Parameters in Jimma Medical Center, Southwest Ethiopia: A Cross-Sectional Study |
title_sort |
prevalence of leukemia and associated factors among patients with abnormal hematological parameters in jimma medical center, southwest ethiopia: a cross-sectional study |
publisher |
Hindawi Limited |
series |
Advances in Hematology |
issn |
1687-9104 1687-9112 |
publishDate |
2020-01-01 |
description |
Introduction. Leukemia is a heterogeneous group of hematological disorder which comprise several diverse and biologically distinct subgroups. Leukemia represents the 11th and 10th most frequent cause of cancer morbidity and mortality worldwide, respectively. Adequate data regarding the prevalence of leukemia are lacking in Ethiopia, particularly in the study area. This study is aimed to determine the prevalence of leukemia and associated factors among patients who have abnormal hematological parameters in Jimma Medical Center. Methodology. A facility-based cross-sectional study was conducted involving 332 patients who have abnormal hematological parameters. Complete blood count from venous blood was made with Sysmex autohematology analyzer (Sysmex XS-500i and XT-1800; Kobe, Japan). Peripheral blood morphology and bone marrow aspirate examination were done for each patient. Descriptive statistics for the prevalence of leukemia and multinomial logistic regression analysis to assess associated factors were executed with IBM SPSS version 25. Results. The prevalence of leukemia was 9.3%, while acute myeloid leukemia, Acute Lymphoid Leukemia, Chronic Myeloid Leukemia, Chronic Lymphoid Leukemia, Myelodysplastic Syndrome, and undifferentiated leukemia comprises 3.6%, 2.7%, 1.8%, 0.6%, and 0.3%, respectively. Older Age (p=0.019), being male (p=0.047), being anemic (p=0.03), and rural residency of a patient (p=0.044) were significantly associated with having acute myeloid leukemia. Conclusion. The prevalence of leukemia among patients who have abnormal hematological parameters in Jimma Medical Center is significant which needs further comprehensive investigations of the associated factors and predictors with more up to date diagnostic methods. |
url |
http://dx.doi.org/10.1155/2020/2014152 |
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