Human umbilical cord Wharton jelly cells promote extra-pancreatic insulin formation and repair of renal damage in STZ-induced diabetic mice
Abstract Background We evaluated the therapeutic effect and fate of high doses of human umbilical cord Wharton jelly cells (hUCWJCs) after IP administration to streptozotocin (STZ)-induced diabetic mice. Methods Type 1 diabetes (T1D) was induced in Kunming mice via IP injection of STZ. hUCWJCs were...
Main Authors: | Martin Maldonado, Tianhua Huang, Lujun Yang, Lan Xu, Lian Ma |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-10-01
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Series: | Cell Communication and Signaling |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12964-017-0199-5 |
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