Human umbilical cord Wharton jelly cells promote extra-pancreatic insulin formation and repair of renal damage in STZ-induced diabetic mice

Human umbilical cord Wharton jelly cells promote extra-pancreatic insulin formation and repair of renal damage in STZ-induced diabetic mice

Abstract Background We evaluated the therapeutic effect and fate of high doses of human umbilical cord Wharton jelly cells (hUCWJCs) after IP administration to streptozotocin (STZ)-induced diabetic mice. Methods Type 1 diabetes (T1D) was induced in Kunming mice via IP injection of STZ. hUCWJCs were...

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Bibliographic Details
Main Authors: Martin Maldonado, Tianhua Huang, Lujun Yang, Lan Xu, Lian Ma
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Cell Communication and Signaling
Subjects:
Human umbilical cord Wharton jelly cells
Diabetes type-1
Streptozotocin
Intraperitoneal administration
Insulin
Online Access:http://link.springer.com/article/10.1186/s12964-017-0199-5

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