Pathological Femoral Fracture due to Osteoporosis and Hypophosphatemic Osteomalacia Following Adefovir Therapy in a Patient with Chronic Hepatitis B
Adefovir dipivoxil (ADV) is a nucleotide analogue used in the chronic hepatitis B treatment. Proximal renal tubular dysfunction is one of the adverse effects of this agent and characterized with hypophosphatemia and osteomalacia. However, reduced bone mineral density with fracture due to ADV therapy...
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Galenos Yayinevi
2018-08-01
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| Series: | Türk Osteoporoz Dergisi |
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| Online Access: | http://cms.galenos.com.tr/Uploads/Article_19913/TOD-24-59-En.pdf |
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doaj-1621aafdb31d4765b096e3272a713c272020-11-25T04:07:23ZengGalenos YayineviTürk Osteoporoz Dergisi2147-26532018-08-01242596210.4274/tod.04796Pathological Femoral Fracture due to Osteoporosis and Hypophosphatemic Osteomalacia Following Adefovir Therapy in a Patient with Chronic Hepatitis BSevilay Batıbay0Duygu Geler Külcü1Nilgün Mesci2Borçak Çağlar Ruhi3Zerrin Şahin4Hasan Gündoğdu5İstanbul Haydarpaşa Numune Training and Research Hospital, Clinic of Physical Medicine and Rehabilitation, İstanbul, Turkeyİstanbul Haydarpaşa Numune Training and Research Hospital, Clinic of Physical Medicine and Rehabilitation, İstanbul, Turkeyİstanbul Haydarpaşa Numune Training and Research Hospital, Clinic of Physical Medicine and Rehabilitation, İstanbul, Turkeyİstanbul Haydarpaşa Numune Training and Research Hospital, Clinic of Nephrology, İstanbul, Turkeyİstanbul Haydarpaşa Numune Training and Research Hospital, Clinic of Physical Medicine and Rehabilitation, İstanbul, TurkeyArtvin State Hospital, Clinic of Radiology, Artvin, TurkeyAdefovir dipivoxil (ADV) is a nucleotide analogue used in the chronic hepatitis B treatment. Proximal renal tubular dysfunction is one of the adverse effects of this agent and characterized with hypophosphatemia and osteomalacia. However, reduced bone mineral density with fracture due to ADV therapy has not been reported before. We aimed to report a 55-year-old male patient with proximal femur fracture who developed hypophosphatemic osteomalacia while using low dose of adefovir (10 mg/day) for chronic hepatitis B treatment for 10 years.http://cms.galenos.com.tr/Uploads/Article_19913/TOD-24-59-En.pdfAdefovir dipivoxilhypophosphatemiaosteomalaciaosteoporosisfracture |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Sevilay Batıbay Duygu Geler Külcü Nilgün Mesci Borçak Çağlar Ruhi Zerrin Şahin Hasan Gündoğdu |
| spellingShingle |
Sevilay Batıbay Duygu Geler Külcü Nilgün Mesci Borçak Çağlar Ruhi Zerrin Şahin Hasan Gündoğdu Pathological Femoral Fracture due to Osteoporosis and Hypophosphatemic Osteomalacia Following Adefovir Therapy in a Patient with Chronic Hepatitis B Türk Osteoporoz Dergisi Adefovir dipivoxil hypophosphatemia osteomalacia osteoporosis fracture |
| author_facet |
Sevilay Batıbay Duygu Geler Külcü Nilgün Mesci Borçak Çağlar Ruhi Zerrin Şahin Hasan Gündoğdu |
| author_sort |
Sevilay Batıbay |
| title |
Pathological Femoral Fracture due to Osteoporosis and Hypophosphatemic Osteomalacia Following Adefovir Therapy in a Patient with Chronic Hepatitis B |
| title_short |
Pathological Femoral Fracture due to Osteoporosis and Hypophosphatemic Osteomalacia Following Adefovir Therapy in a Patient with Chronic Hepatitis B |
| title_full |
Pathological Femoral Fracture due to Osteoporosis and Hypophosphatemic Osteomalacia Following Adefovir Therapy in a Patient with Chronic Hepatitis B |
| title_fullStr |
Pathological Femoral Fracture due to Osteoporosis and Hypophosphatemic Osteomalacia Following Adefovir Therapy in a Patient with Chronic Hepatitis B |
| title_full_unstemmed |
Pathological Femoral Fracture due to Osteoporosis and Hypophosphatemic Osteomalacia Following Adefovir Therapy in a Patient with Chronic Hepatitis B |
| title_sort |
pathological femoral fracture due to osteoporosis and hypophosphatemic osteomalacia following adefovir therapy in a patient with chronic hepatitis b |
| publisher |
Galenos Yayinevi |
| series |
Türk Osteoporoz Dergisi |
| issn |
2147-2653 |
| publishDate |
2018-08-01 |
| description |
Adefovir dipivoxil (ADV) is a nucleotide analogue used in the chronic hepatitis B treatment. Proximal renal tubular dysfunction is one of the adverse effects of this agent and characterized with hypophosphatemia and osteomalacia. However, reduced bone mineral density with fracture due to ADV therapy has not been reported before. We aimed to report a 55-year-old male patient with proximal femur fracture who developed hypophosphatemic osteomalacia while using low dose of adefovir (10 mg/day) for chronic hepatitis B treatment for 10 years. |
| topic |
Adefovir dipivoxil hypophosphatemia osteomalacia osteoporosis fracture |
| url |
http://cms.galenos.com.tr/Uploads/Article_19913/TOD-24-59-En.pdf |
| work_keys_str_mv |
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