Blue light regenerates functional visual pigments in mammals through a retinyl-phospholipid intermediate

Blue light regenerates functional visual pigments in mammals through a retinyl-phospholipid intermediate

It is currently thought that visual pigments in vertebrate photoreceptors are regenerated exclusively through enzymatic cycles. Here the authors show that mammalian photoreceptors also regenerate opsin pigments in light through photoisomerization of N-ret-PE (N-retinylidene-phosphatidylethanolamine.

Bibliographic Details
Main Authors: Joanna J. Kaylor, Tongzhou Xu, Norianne T. Ingram, Avian Tsan, Hayk Hakobyan, Gordon L. Fain, Gabriel H. Travis
Format: Article
Language:English
Published: Nature Publishing Group 2017-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-00018-4
Description
Summary:It is currently thought that visual pigments in vertebrate photoreceptors are regenerated exclusively through enzymatic cycles. Here the authors show that mammalian photoreceptors also regenerate opsin pigments in light through photoisomerization of N-ret-PE (N-retinylidene-phosphatidylethanolamine.
ISSN:2041-1723

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