Calcium Ion Detection Using Miniaturized InN-based Ion Sensitive Field Effect Transistors
An Ultrathin (~10 nm) InN ion sensitive field effect transistor (ISFET) with gate regions functionalized with phosphotyrosine (p-Tyr) is proposed to detect calcium ions (Ca<sup>2+</sup>) in aqueous solution. The ISFET was miniaturized to a chip size of 1.1 mm by 1.5 mm and integrated at...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Chinese Institute of Automation Engineers (CIAE) & Taiwan Smart Living Space Association (SMART LISA)
2012-03-01
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| Series: | International Journal of Automation and Smart Technology |
| Subjects: | |
| Online Access: | http://www.ausmt.org/index.php/AUSMT/article/view/117 |
| Summary: | An Ultrathin (~10 nm) InN ion sensitive field effect transistor (ISFET) with gate regions functionalized with phosphotyrosine (p-Tyr) is proposed to detect calcium ions (Ca<sup>2+</sup>) in aqueous solution. The ISFET was miniaturized to a chip size of 1.1 mm by 1.5 mm and integrated at the tip of a hypodermic injection needle (18 G) for real-time and continuous monitoring. The sensor shows a current variation ratio of 1.11% with per decade change of Ca<sup>2+</sup> and a detection limit of 10-6 M. The response time of 5 sec. reveals its great potential for accomplishing fast detection in chemical and physiological sensing applications. The sensor would be applied in medical diagnosis and used to monitor continuous and real-time variations of Ca<sup>2+</sup> levels in human blood in the near future.<br /> |
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| ISSN: | 2223-9766 |