Kinetics of antibody responses to PfRH5-complex antigens in Ghanaian children with Plasmodium falciparum malaria.
Plasmodium falciparum PfRH5 protein binds Ripr, CyRPA and Pf113 to form a complex that is essential for merozoite invasion of erythrocytes. The inter-genomic conservation of the PfRH5 complex proteins makes them attractive blood stage vaccine candidates. However, little is known about how antibodies...
Main Authors: | Frederica D Partey, Filip C Castberg, Edem W Sarbah, Sarah E Silk, Gordon A Awandare, Simon J Draper, Nicholas Opoku, Margaret Kweku, Michael F Ofori, Lars Hviid, Lea Barfod |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5993283?pdf=render |
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