Oral vancomycin desensitisation to treat Clostridium difficile infection in a vancomycin allergic patient

The prevalence of Clostridium difficile infection (CDI) is increasing worldwide. Oral vancomycin is an effective and frequently used treatment. However, patients with CDI who are allergic to intravenous vancomycin cannot receive oral vancomycin due to the risk of anaphylaxis if given the oral form.W...

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Bibliographic Details
Main Authors: Shanti Mahabir, Ren Yik Lim, Fidelma Fitzpatrick, Colm Magee, Mary Keogan
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:World Allergy Organization Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S1939455119306386
Description
Summary:The prevalence of Clostridium difficile infection (CDI) is increasing worldwide. Oral vancomycin is an effective and frequently used treatment. However, patients with CDI who are allergic to intravenous vancomycin cannot receive oral vancomycin due to the risk of anaphylaxis if given the oral form.We present a case where oral vancomycin desensitisation was used to successfully treat a vancomycin allergic patient with recurrent CDI. Keywords: Allergy, Anaphylaxis, Desensitisation, Vancomycin, Clostridium difficile
ISSN:1939-4551