Vildagliptin Can Alleviate Endoplasmic Reticulum Stress in the Liver Induced by a High Fat Diet
Purpose. We investigated whether a DDP-4 inhibitor, vildagliptin, alleviated ER stress induced by a high fat diet and improved hepatic lipid deposition. Methods. C57BL/6 mice received standard chow diet (CD), high fat diet (HFD), and HFD administered with vildagliptin (50 mg/Kg) (V-HFD). After admin...
Main Authors: | Xiaoqing Ma, Wenhua Du, Shanshan Shao, Chunxiao Yu, Lingyan Zhou, Fei Jing |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2018-01-01
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Series: | BioMed Research International |
Online Access: | http://dx.doi.org/10.1155/2018/5045182 |
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