Assessment of Factor VII Levels in Patients of Chronic Liver Disease
Background : To determine the levels of coagulation factor VII in patients of chronic liver disease. Methods: In this descriptive study sixty known patients of chronic liver disease were included. Patients were stratified into three groups on the basis of Child-Pugh scoring system, utilizing ascite...
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| Format: | Article |
| Language: | English |
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Rawalpindi Medical University
2013-06-01
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| Series: | Journal of Rawalpindi Medical College |
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| Online Access: | https://www.journalrmc.com/index.php/JRMC/article/view/499 |
| Summary: | Background : To determine the levels of coagulation factor VII in patients of chronic liver disease.
Methods: In this descriptive study sixty known patients of chronic liver disease were included. Patients were stratified into three groups on the basis of Child-Pugh scoring system, utilizing ascites, bilirubin, albumin, prothrombin time and encephalopathy as markers of disease activity. The correlation of Child-Pugh scoring system with factor VII levels was analyzed
Results: Majority ( 63.33%) were males . Mean age was 50.5 years. Majority of patients (82%) had deficient Factor VII levels. Factor VII levels revealed a declining trend from Child-Pugh class B to C.
Conclusion: Due to its short half-life factor VII level can serve as a helpful marker in diagnosing the degree of liver damage and as a prognostic indicator during the course of treatment.
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| ISSN: | 1683-3562 1683-3570 |