Leprosy of the Larynx: A Case Report
Leprosy is an ancient deforming disease caused by Mycobacterium leprae, which is still poorly understood and often feared by the general public and even by some in the health care professions Fortunately, the outlook for patients has dramatically improved over the last three decades with the introdu...
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Tehran University of Medical Sciences
2009-12-01
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doaj-16bc69ba8fd94e4bb159a008f9b917702020-11-25T03:52:01ZengTehran University of Medical SciencesActa Medica Iranica0044-60250173-59692009-12-01476485487Leprosy of the Larynx: A Case ReportMansoureh Momen HeraviAlireza SharifLeprosy is an ancient deforming disease caused by Mycobacterium leprae, which is still poorly understood and often feared by the general public and even by some in the health care professions Fortunately, the outlook for patients has dramatically improved over the last three decades with the introduction of multi-drug treatment and management strategies that have somewhat diminished the stigma of this diagnosis. We report a rare case of leprosy of larynx. A 45 year old man presented with complaints cough, dyspnea and hoarseness since many years ago. Because of demonstration of acid fast bacilli in smear of his sputum, the diagnosis of tuberculosis was made and anti tuberculosis treatment was initiated. But he developed fever and his symptoms exacerbated. In examination there was a tender erythematous nodule on right supraclavicular region, loss of eyebrows and lashes and disseminated hyper and hypo pigmented cutaneous lesions on abdomen, thorax, back with normal chest x ray. Laryngoscopy to rule out laryngeal tuberculosis was done and granulomatous lesion was seen. Laryngeal and skin biopsy was performed which numerous acid fast bacilli, macrophages and foamy cells suggestive of lepromatous leprosy were demonstrated in both specimens. Treatment was started on multi bacillary regime of WHO multidrug therapy. In conclusion, this report highlights the importance of systemic involvement in lepromatous leprosy especially when the initial presentation is laryngitis or respiratory symptoms. Laryngeal leprosy may mistaken with tuberculosis laryngitis due to respiratory problems and existence of acid fast bacilli in respiratory secretions.http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/14860.pdf&manuscript_id=14860LeprosyLaryngitisLarynxMycobacteriumLeprae |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Mansoureh Momen Heravi Alireza Sharif |
spellingShingle |
Mansoureh Momen Heravi Alireza Sharif Leprosy of the Larynx: A Case Report Acta Medica Iranica Leprosy Laryngitis Larynx Mycobacterium Leprae |
author_facet |
Mansoureh Momen Heravi Alireza Sharif |
author_sort |
Mansoureh Momen Heravi |
title |
Leprosy of the Larynx: A Case Report |
title_short |
Leprosy of the Larynx: A Case Report |
title_full |
Leprosy of the Larynx: A Case Report |
title_fullStr |
Leprosy of the Larynx: A Case Report |
title_full_unstemmed |
Leprosy of the Larynx: A Case Report |
title_sort |
leprosy of the larynx: a case report |
publisher |
Tehran University of Medical Sciences |
series |
Acta Medica Iranica |
issn |
0044-6025 0173-5969 |
publishDate |
2009-12-01 |
description |
Leprosy is an ancient deforming disease caused by Mycobacterium leprae, which is still poorly understood and often feared by the general public and even by some in the health care professions Fortunately, the outlook for patients has dramatically improved over the last three decades with the introduction of multi-drug treatment and management strategies that have somewhat diminished the stigma of this diagnosis. We report a rare case of leprosy of larynx. A 45 year old man presented with complaints cough, dyspnea and hoarseness since many years ago. Because of demonstration of acid fast bacilli in smear of his sputum, the diagnosis of tuberculosis was made and anti tuberculosis treatment was initiated. But he developed fever and his symptoms exacerbated. In examination there was a tender erythematous nodule on right supraclavicular region, loss of eyebrows and lashes and disseminated hyper and hypo pigmented cutaneous lesions on abdomen, thorax, back with normal chest x ray. Laryngoscopy to rule out laryngeal tuberculosis was done and granulomatous lesion was seen. Laryngeal and skin biopsy was performed which numerous acid fast bacilli, macrophages and foamy cells suggestive of lepromatous leprosy were demonstrated in both specimens. Treatment was started on multi bacillary regime of WHO multidrug therapy. In conclusion, this report highlights the importance of systemic involvement in lepromatous leprosy especially when the initial presentation is laryngitis or respiratory symptoms. Laryngeal leprosy may mistaken with tuberculosis laryngitis due to respiratory problems and existence of acid fast bacilli in respiratory secretions. |
topic |
Leprosy Laryngitis Larynx Mycobacterium Leprae |
url |
http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/14860.pdf&manuscript_id=14860 |
work_keys_str_mv |
AT mansourehmomenheravi leprosyofthelarynxacasereport AT alirezasharif leprosyofthelarynxacasereport |
_version_ |
1724484939831836672 |