Metabolic syndrome and the plasma proteome: from association to causation

Metabolic syndrome and the plasma proteome: from association to causation

Abstract Background The metabolic syndrome (MetS), defined by the simultaneous clustering of cardio-metabolic risk factors, is a significant worldwide public health burden with an estimated 25% prevalence worldwide. The pathogenesis of MetS is not entirely clear and the use of molecular level data c...

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Main Authors: Mohamed A. Elhadad, Rory Wilson, Shaza B. Zaghlool, Cornelia Huth, Christian Gieger, Harald Grallert, Johannes Graumann, Wolfgang Rathmann, Wolfgang Koenig, Moritz F. Sinner, Kristian Hveem, Karsten Suhre, Barbara Thorand, Christian Jonasson, Melanie Waldenberger, Annette Peters
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Cardiovascular Diabetology
Subjects:
Metabolic syndrome
Proteomics
Blood proteins
Mendelian randomization analysis
Diabetes mellitus
type 2
Online Access:https://doi.org/10.1186/s12933-021-01299-2

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