Potential Therapeutic Benefit of Combining Gefitinib and Tamoxifen for Treating Advanced Lung Adenocarcinoma

Introduction. Epidermal growth factor receptor (EGFR) mutations are known as oncogene driver mutations and with EGFR mutations exhibit good response to the EGFR tyrosine kinase inhibitor Gefitinib. Some studies have shown that activation of estrogen and estrogen receptor α or β (ERα/β) promote adeno...

Full description

Bibliographic Details
Main Authors: Chien-Ming Liu, Kuo-Liang Chiu, Tzu-Sheng Chen, Shang-Miao Chang, Shu-Yun Yang, Li-Hsiou Chen, Yung-Lun Ni, Yuh-Pyng Sher, Sung-Liang Yu, Wen-Lung Ma
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/642041