Atf3 mutant mice show reduced axon regeneration and impaired regeneration-associated gene induction after peripheral nerve injury
Axon injury in the peripheral nervous system (PNS) induces a regeneration-associated gene (RAG) response. Atf3 (activating transcription factor 3) is such a RAG and ATF3's transcriptional activity might induce ‘effector’ RAGs (e.g. small proline rich protein 1a (Sprr1a), Galanin (Gal), growth-a...
Main Authors: | Manuel Gey, Renate Wanner, Corinna Schilling, Maria T. Pedro, Daniela Sinske, Bernd Knöll |
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Format: | Article |
Language: | English |
Published: |
The Royal Society
2016-01-01
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Series: | Open Biology |
Subjects: | |
Online Access: | https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.160091 |
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