Pulmonary Protection Strategies in Cardiac Surgery: Are We Making Any Progress?
Pulmonary dysfunction is a common complication of cardiac surgery. The mechanisms involved in the development of pulmonary dysfunction are multifactorial and can be related to the activation of inflammatory and oxidative stress pathways. Clinical manifestation varies from mild atelectasis to severe...
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2015-01-01
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Series: | Oxidative Medicine and Cellular Longevity |
Online Access: | http://dx.doi.org/10.1155/2015/416235 |
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doaj-16e7995c35334fe7ad6036ab8d6264852020-11-24T22:25:11ZengHindawi LimitedOxidative Medicine and Cellular Longevity1942-09001942-09942015-01-01201510.1155/2015/416235416235Pulmonary Protection Strategies in Cardiac Surgery: Are We Making Any Progress?Emad Al Jaaly0Mustafa Zakkar1Francesca Fiorentino2Gianni D. Angelini3Bristol Heart Institute, Bristol Royal Infirmary, Upper Maudlin Street, Bristol BS2 8HW, UKBristol Heart Institute, Bristol Royal Infirmary, Upper Maudlin Street, Bristol BS2 8HW, UKCardiac Surgery, National Heart and Lung Institute, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0HS, UKBristol Heart Institute, Bristol Royal Infirmary, Upper Maudlin Street, Bristol BS2 8HW, UKPulmonary dysfunction is a common complication of cardiac surgery. The mechanisms involved in the development of pulmonary dysfunction are multifactorial and can be related to the activation of inflammatory and oxidative stress pathways. Clinical manifestation varies from mild atelectasis to severe respiratory failure. Managing pulmonary dysfunction postcardiac surgery is a multistep process that starts before surgery and continues during both the operative and postoperative phases. Different pulmonary protection strategies have evolved over the years; however, the wide acceptance and clinical application of such techniques remain hindered by the poor level of evidence or the sample size of the studies. A better understanding of available modalities and/or combinations can result in the development of customised strategies for the different cohorts of patients with the potential to hence maximise patients and institutes benefits.http://dx.doi.org/10.1155/2015/416235 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Emad Al Jaaly Mustafa Zakkar Francesca Fiorentino Gianni D. Angelini |
spellingShingle |
Emad Al Jaaly Mustafa Zakkar Francesca Fiorentino Gianni D. Angelini Pulmonary Protection Strategies in Cardiac Surgery: Are We Making Any Progress? Oxidative Medicine and Cellular Longevity |
author_facet |
Emad Al Jaaly Mustafa Zakkar Francesca Fiorentino Gianni D. Angelini |
author_sort |
Emad Al Jaaly |
title |
Pulmonary Protection Strategies in Cardiac Surgery: Are We Making Any Progress? |
title_short |
Pulmonary Protection Strategies in Cardiac Surgery: Are We Making Any Progress? |
title_full |
Pulmonary Protection Strategies in Cardiac Surgery: Are We Making Any Progress? |
title_fullStr |
Pulmonary Protection Strategies in Cardiac Surgery: Are We Making Any Progress? |
title_full_unstemmed |
Pulmonary Protection Strategies in Cardiac Surgery: Are We Making Any Progress? |
title_sort |
pulmonary protection strategies in cardiac surgery: are we making any progress? |
publisher |
Hindawi Limited |
series |
Oxidative Medicine and Cellular Longevity |
issn |
1942-0900 1942-0994 |
publishDate |
2015-01-01 |
description |
Pulmonary dysfunction is a common complication of cardiac surgery. The mechanisms involved in the development of pulmonary dysfunction are multifactorial and can be related to the activation of inflammatory and oxidative stress pathways. Clinical manifestation varies from mild atelectasis to severe respiratory failure. Managing pulmonary dysfunction postcardiac surgery is a multistep process that starts before surgery and continues during both the operative and postoperative phases. Different pulmonary protection strategies have evolved over the years; however, the wide acceptance and clinical application of such techniques remain hindered by the poor level of evidence or the sample size of the studies. A better understanding of available modalities and/or combinations can result in the development of customised strategies for the different cohorts of patients with the potential to hence maximise patients and institutes benefits. |
url |
http://dx.doi.org/10.1155/2015/416235 |
work_keys_str_mv |
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