Eco-Friendly Syntheses of 2-Substituted Benzoxazoles and 2-Substituted Benzothiazoles from 2-Aminophenols, 2-Aminothiophenols and DMF Derivatives in the Presence of Imidazolium Chloride
A simple, economical and metal-free approach to the synthesis of 2-substituted benzoxazoles and 2-substituted benzothiazoles from 2-aminophenols, 2-aminothiophenols and DMF derivatives, only using imidazolium chloride (50% mmol) as promoter without any other additive, was reported. Various 2-substit...
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MDPI AG
2019-01-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/24/1/174 |
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doaj-170cb20863d34bfd802a419b9cef8b0f2020-11-25T02:42:01ZengMDPI AGMolecules1420-30492019-01-0124117410.3390/molecules24010174molecules24010174Eco-Friendly Syntheses of 2-Substituted Benzoxazoles and 2-Substituted Benzothiazoles from 2-Aminophenols, 2-Aminothiophenols and DMF Derivatives in the Presence of Imidazolium ChlorideQingqiang Tian0Wen Luo1Zongjie Gan2Dan Li3Zeshu Dai4Huajun Wang5Xuetong Wang6Jianyong Yuan7Department of Medicinal Chemistry, College of Pharmacy, Chongqing Medical University, Chongqing 400016, ChinaDepartment of Medicinal Chemistry, College of Pharmacy, Chongqing Medical University, Chongqing 400016, ChinaDepartment of Medicinal Chemistry, College of Pharmacy, Chongqing Medical University, Chongqing 400016, ChinaDepartment of Medicinal Chemistry, College of Pharmacy, Chongqing Medical University, Chongqing 400016, ChinaDepartment of Medicinal Chemistry, College of Pharmacy, Chongqing Medical University, Chongqing 400016, ChinaDepartment of Medicinal Chemistry, College of Pharmacy, Chongqing Medical University, Chongqing 400016, ChinaDepartment of Medicinal Chemistry, College of Pharmacy, Chongqing Medical University, Chongqing 400016, ChinaDepartment of Medicinal Chemistry, College of Pharmacy, Chongqing Medical University, Chongqing 400016, ChinaA simple, economical and metal-free approach to the synthesis of 2-substituted benzoxazoles and 2-substituted benzothiazoles from 2-aminophenols, 2-aminothiophenols and DMF derivatives, only using imidazolium chloride (50% mmol) as promoter without any other additive, was reported. Various 2-substituted benzoxazoles and 2-substituted benzothiazoles were thus prepared in moderate to excellent yields.http://www.mdpi.com/1420-3049/24/1/174imidazolium chloridebenzoxazoles and benzothiazoles derivativessyntheses |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Qingqiang Tian Wen Luo Zongjie Gan Dan Li Zeshu Dai Huajun Wang Xuetong Wang Jianyong Yuan |
| spellingShingle |
Qingqiang Tian Wen Luo Zongjie Gan Dan Li Zeshu Dai Huajun Wang Xuetong Wang Jianyong Yuan Eco-Friendly Syntheses of 2-Substituted Benzoxazoles and 2-Substituted Benzothiazoles from 2-Aminophenols, 2-Aminothiophenols and DMF Derivatives in the Presence of Imidazolium Chloride Molecules imidazolium chloride benzoxazoles and benzothiazoles derivatives syntheses |
| author_facet |
Qingqiang Tian Wen Luo Zongjie Gan Dan Li Zeshu Dai Huajun Wang Xuetong Wang Jianyong Yuan |
| author_sort |
Qingqiang Tian |
| title |
Eco-Friendly Syntheses of 2-Substituted Benzoxazoles and 2-Substituted Benzothiazoles from 2-Aminophenols, 2-Aminothiophenols and DMF Derivatives in the Presence of Imidazolium Chloride |
| title_short |
Eco-Friendly Syntheses of 2-Substituted Benzoxazoles and 2-Substituted Benzothiazoles from 2-Aminophenols, 2-Aminothiophenols and DMF Derivatives in the Presence of Imidazolium Chloride |
| title_full |
Eco-Friendly Syntheses of 2-Substituted Benzoxazoles and 2-Substituted Benzothiazoles from 2-Aminophenols, 2-Aminothiophenols and DMF Derivatives in the Presence of Imidazolium Chloride |
| title_fullStr |
Eco-Friendly Syntheses of 2-Substituted Benzoxazoles and 2-Substituted Benzothiazoles from 2-Aminophenols, 2-Aminothiophenols and DMF Derivatives in the Presence of Imidazolium Chloride |
| title_full_unstemmed |
Eco-Friendly Syntheses of 2-Substituted Benzoxazoles and 2-Substituted Benzothiazoles from 2-Aminophenols, 2-Aminothiophenols and DMF Derivatives in the Presence of Imidazolium Chloride |
| title_sort |
eco-friendly syntheses of 2-substituted benzoxazoles and 2-substituted benzothiazoles from 2-aminophenols, 2-aminothiophenols and dmf derivatives in the presence of imidazolium chloride |
| publisher |
MDPI AG |
| series |
Molecules |
| issn |
1420-3049 |
| publishDate |
2019-01-01 |
| description |
A simple, economical and metal-free approach to the synthesis of 2-substituted benzoxazoles and 2-substituted benzothiazoles from 2-aminophenols, 2-aminothiophenols and DMF derivatives, only using imidazolium chloride (50% mmol) as promoter without any other additive, was reported. Various 2-substituted benzoxazoles and 2-substituted benzothiazoles were thus prepared in moderate to excellent yields. |
| topic |
imidazolium chloride benzoxazoles and benzothiazoles derivatives syntheses |
| url |
http://www.mdpi.com/1420-3049/24/1/174 |
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