DNA Methylation Regulator-Meditated Modification Patterns Define the Distinct Tumor Microenvironment in Lung Adenocarcinoma

DNA Methylation Regulator-Meditated Modification Patterns Define the Distinct Tumor Microenvironment in Lung Adenocarcinoma

BackgroundEpigenetic changes of lung adenocarcinoma (LUAD) have been reported to be a relevant factor in tumorigenesis and cancer progression. However, the molecular mechanisms responsible for DNA methylation patterns in the tumor immune-infiltrating microenvironment and in cancer immunotherapy rema...

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Bibliographic Details
Main Authors: Didi Yuan, Zehong Wei, Yicheng Wang, Fang Cheng, Yujie Zeng, Li Yang, Shangyu Zhang, Jianbo Li, Renkuan Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Oncology
Subjects:
lung adenocarcinoma (LUAD)
DNA methylation
tumor microenvironment
immunotherapy
mutation burden
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.734873/full

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