Avian Stress-Related Transcriptome and Selenotranscriptome: Role during Exposure to Heavy Metals and Heat Stress

Selenium, through incorporation into selenoproteins, is one of the key elements of the antioxidant system. Over the past few years there has been increased interest in exploring those molecular mechanisms in chicken, responsible for the development of this protection system. In more detail, Cd/Pb po...

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Main Authors:	Isidoros Seremelis, Georgios P. Danezis, Athanasios C. Pappas, Evangelos Zoidis, Kostas Fegeros
Format:	Article
Language:	English
Published:	MDPI AG 2019-07-01
Series:	Antioxidants
Subjects:	Animal health heat stress heavy metals selenium selenoprotein selenotranscriptome
Online Access:	https://www.mdpi.com/2076-3921/8/7/216

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spelling	doaj-1725a7c6024f4d4d9c4a21a08e49cffa2020-11-24T20:44:10ZengMDPI AGAntioxidants2076-39212019-07-018721610.3390/antiox8070216antiox8070216Avian Stress-Related Transcriptome and Selenotranscriptome: Role during Exposure to Heavy Metals and Heat StressIsidoros Seremelis0Georgios P. Danezis1Athanasios C. Pappas2Evangelos Zoidis3Kostas Fegeros4Chemistry Laboratory, Department of Food Science and Human Nutrition, Agricultural University of Athens, 75 Iera Odos, 11855 Athens, GreeceChemistry Laboratory, Department of Food Science and Human Nutrition, Agricultural University of Athens, 75 Iera Odos, 11855 Athens, GreeceDepartment of Nutritional Physiology and Feeding, Faculty of Animal Science, Agricultural University of Athens, 75 Iera Odos, 11855 Athens, GreeceDepartment of Nutritional Physiology and Feeding, Faculty of Animal Science, Agricultural University of Athens, 75 Iera Odos, 11855 Athens, GreeceDepartment of Nutritional Physiology and Feeding, Faculty of Animal Science, Agricultural University of Athens, 75 Iera Odos, 11855 Athens, GreeceSelenium, through incorporation into selenoproteins, is one of the key elements of the antioxidant system. Over the past few years there has been increased interest in exploring those molecular mechanisms in chicken, responsible for the development of this protection system. In more detail, Cd/Pb poisoning and heat stress increase oxidation, mRNA levels of inflammatory proteins, and apoptotic proteins. Selenium seems to enhance the antioxidant status and alleviates these effects via upregulation of antioxidant proteins and other molecular effects. In this review, we analyze avian transcriptome key elements with particular emphasis on interactions with heavy metals and on relation to heat stress.https://www.mdpi.com/2076-3921/8/7/216Animal healthheat stressheavy metalsseleniumselenoproteinselenotranscriptome
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Isidoros Seremelis Georgios P. Danezis Athanasios C. Pappas Evangelos Zoidis Kostas Fegeros
spellingShingle	Isidoros Seremelis Georgios P. Danezis Athanasios C. Pappas Evangelos Zoidis Kostas Fegeros Avian Stress-Related Transcriptome and Selenotranscriptome: Role during Exposure to Heavy Metals and Heat Stress Antioxidants Animal health heat stress heavy metals selenium selenoprotein selenotranscriptome
author_facet	Isidoros Seremelis Georgios P. Danezis Athanasios C. Pappas Evangelos Zoidis Kostas Fegeros
author_sort	Isidoros Seremelis
title	Avian Stress-Related Transcriptome and Selenotranscriptome: Role during Exposure to Heavy Metals and Heat Stress
title_short	Avian Stress-Related Transcriptome and Selenotranscriptome: Role during Exposure to Heavy Metals and Heat Stress
title_full	Avian Stress-Related Transcriptome and Selenotranscriptome: Role during Exposure to Heavy Metals and Heat Stress
title_fullStr	Avian Stress-Related Transcriptome and Selenotranscriptome: Role during Exposure to Heavy Metals and Heat Stress
title_full_unstemmed	Avian Stress-Related Transcriptome and Selenotranscriptome: Role during Exposure to Heavy Metals and Heat Stress
title_sort	avian stress-related transcriptome and selenotranscriptome: role during exposure to heavy metals and heat stress
publisher	MDPI AG
series	Antioxidants
issn	2076-3921
publishDate	2019-07-01
description	Selenium, through incorporation into selenoproteins, is one of the key elements of the antioxidant system. Over the past few years there has been increased interest in exploring those molecular mechanisms in chicken, responsible for the development of this protection system. In more detail, Cd/Pb poisoning and heat stress increase oxidation, mRNA levels of inflammatory proteins, and apoptotic proteins. Selenium seems to enhance the antioxidant status and alleviates these effects via upregulation of antioxidant proteins and other molecular effects. In this review, we analyze avian transcriptome key elements with particular emphasis on interactions with heavy metals and on relation to heat stress.
topic	Animal health heat stress heavy metals selenium selenoprotein selenotranscriptome
url	https://www.mdpi.com/2076-3921/8/7/216
work_keys_str_mv	AT isidorosseremelis avianstressrelatedtranscriptomeandselenotranscriptomeroleduringexposuretoheavymetalsandheatstress AT georgiospdanezis avianstressrelatedtranscriptomeandselenotranscriptomeroleduringexposuretoheavymetalsandheatstress AT athanasioscpappas avianstressrelatedtranscriptomeandselenotranscriptomeroleduringexposuretoheavymetalsandheatstress AT evangeloszoidis avianstressrelatedtranscriptomeandselenotranscriptomeroleduringexposuretoheavymetalsandheatstress AT kostasfegeros avianstressrelatedtranscriptomeandselenotranscriptomeroleduringexposuretoheavymetalsandheatstress
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Avian Stress-Related Transcriptome and Selenotranscriptome: Role during Exposure to Heavy Metals and Heat Stress

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