Magnesium depletion extends fission yeast lifespan via general amino acid control activation

Magnesium depletion extends fission yeast lifespan via general amino acid control activation

Abstract Nutrients including glucose, nitrogen, sulfur, zinc, and iron are involved in the regulation of chronological lifespan (CLS) of yeast, which serves as a model of the lifespan of differentiated cells of higher organisms. Herein, we show that magnesium (Mg2+) depletion extends CLS of the fiss...

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Bibliographic Details
Main Authors: Hokuto Ohtsuka, Mikuto Kobayashi, Takafumi Shimasaki, Teppei Sato, Genki Akanuma, Yasuyuki Kitaura, Yoko Otsubo, Akira Yamashita, Hirofumi Aiba
Format: Article
Language:English
Published: Wiley 2021-04-01
Series:MicrobiologyOpen
Subjects:
chronological lifespan
Ecl1 family gene
fission yeast
GAAC
magnesium
Online Access:https://doi.org/10.1002/mbo3.1176

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