Enhancement of phenolics content and biological activities of longan (Dimocarpus longan Lour.) treated with thermal and ageing process
Abstract This study is the first to compare the chemical compositions and biological activities of a conventional dried Dimocarpus longan with a novel black D. longan that underwent a thermal ageing process. Pericarp, aril, and seed of both D. longan were macerated in 95% v/v ethanol. Their chemical...
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2021-08-01
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doaj-17331e8b52a54c8da46d752cd720d29b2021-08-08T11:26:10ZengNature Publishing GroupScientific Reports2045-23222021-08-0111111310.1038/s41598-021-95605-3Enhancement of phenolics content and biological activities of longan (Dimocarpus longan Lour.) treated with thermal and ageing processPreaploy Hong-in0Waranya Neimkhum1Chanun Punyoyai2Suwannee Sriyab3Wantida Chaiyana4Master’s Degree Program in Cosmetic Science, Faculty of Pharmacy, Chiang Mai UniversityDepartment of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, Huachiew Chalermprakiet UniversityDepartment of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai UniversityDepartment of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai UniversityDepartment of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai UniversityAbstract This study is the first to compare the chemical compositions and biological activities of a conventional dried Dimocarpus longan with a novel black D. longan that underwent a thermal ageing process. Pericarp, aril, and seed of both D. longan were macerated in 95% v/v ethanol. Their chemical compositions were investigated using a Folin–Ciocalteu assay, aluminum chloride assay, and high-performance liquid chromatography. Antioxidant activities were evaluated in terms of radical scavenging and iron (III) reduction capacity. An enzyme inhibition assay was used to evaluate the hyaluronidase inhibition. Inflammatory cytokine secretion was evaluated with an enzyme-linked immunosorbent assay. After being exposed to a heating and ageing procedure, gallic acid and ellagic acid content were increased tenfold, while the corilagin content was doubled. Black D. longan seed extract was the most potent anti-hyaluronidase and antioxidant with the strongest free radical scavenging and reduction power, while black D. longan aril extract resulted in the highest inhibition of inflammatory cytokine secretion. Black D. longan contained more biologically active compounds and possessed more potent biological activities than conventional dried D. longan. Therefore, thermal ageing treatment is suggested for producing black D. longan, for which seed extract is suggested as a cosmeceutical active ingredient and aril extract for anti-inflammation.https://doi.org/10.1038/s41598-021-95605-3 |
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DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Preaploy Hong-in Waranya Neimkhum Chanun Punyoyai Suwannee Sriyab Wantida Chaiyana |
spellingShingle |
Preaploy Hong-in Waranya Neimkhum Chanun Punyoyai Suwannee Sriyab Wantida Chaiyana Enhancement of phenolics content and biological activities of longan (Dimocarpus longan Lour.) treated with thermal and ageing process Scientific Reports |
author_facet |
Preaploy Hong-in Waranya Neimkhum Chanun Punyoyai Suwannee Sriyab Wantida Chaiyana |
author_sort |
Preaploy Hong-in |
title |
Enhancement of phenolics content and biological activities of longan (Dimocarpus longan Lour.) treated with thermal and ageing process |
title_short |
Enhancement of phenolics content and biological activities of longan (Dimocarpus longan Lour.) treated with thermal and ageing process |
title_full |
Enhancement of phenolics content and biological activities of longan (Dimocarpus longan Lour.) treated with thermal and ageing process |
title_fullStr |
Enhancement of phenolics content and biological activities of longan (Dimocarpus longan Lour.) treated with thermal and ageing process |
title_full_unstemmed |
Enhancement of phenolics content and biological activities of longan (Dimocarpus longan Lour.) treated with thermal and ageing process |
title_sort |
enhancement of phenolics content and biological activities of longan (dimocarpus longan lour.) treated with thermal and ageing process |
publisher |
Nature Publishing Group |
series |
Scientific Reports |
issn |
2045-2322 |
publishDate |
2021-08-01 |
description |
Abstract This study is the first to compare the chemical compositions and biological activities of a conventional dried Dimocarpus longan with a novel black D. longan that underwent a thermal ageing process. Pericarp, aril, and seed of both D. longan were macerated in 95% v/v ethanol. Their chemical compositions were investigated using a Folin–Ciocalteu assay, aluminum chloride assay, and high-performance liquid chromatography. Antioxidant activities were evaluated in terms of radical scavenging and iron (III) reduction capacity. An enzyme inhibition assay was used to evaluate the hyaluronidase inhibition. Inflammatory cytokine secretion was evaluated with an enzyme-linked immunosorbent assay. After being exposed to a heating and ageing procedure, gallic acid and ellagic acid content were increased tenfold, while the corilagin content was doubled. Black D. longan seed extract was the most potent anti-hyaluronidase and antioxidant with the strongest free radical scavenging and reduction power, while black D. longan aril extract resulted in the highest inhibition of inflammatory cytokine secretion. Black D. longan contained more biologically active compounds and possessed more potent biological activities than conventional dried D. longan. Therefore, thermal ageing treatment is suggested for producing black D. longan, for which seed extract is suggested as a cosmeceutical active ingredient and aril extract for anti-inflammation. |
url |
https://doi.org/10.1038/s41598-021-95605-3 |
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