Mitogen-Activated Protein Kinase Cross-Talk Interaction Modulates the Production of Melanins in Aspergillus fumigatus

Mitogen-Activated Protein Kinase Cross-Talk Interaction Modulates the Production of Melanins in Aspergillus fumigatus

Aspergillus fumigatus is the most important airborne human pathogenic fungus, causing thousands of deaths per year. Its lethality is due to late and often inaccurate diagnosis and the lack of efficient therapeutics. The failure of efficient prophylaxis and therapy is based on the ability of this pat...

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Bibliographic Details
Main Authors: Adriana Oliveira Manfiolli, Filipe Silva Siqueira, Thaila Fernanda dos Reis, Patrick Van Dijck, Sanne Schrevens, Sandra Hoefgen, Martin Föge, Maria Straßburger, Leandro José de Assis, Thorsten Heinekamp, Marina Campos Rocha, Slavica Janevska, Axel A. Brakhage, Iran Malavazi, Gustavo H. Goldman, Vito Valiante
Format: Article
Language:English
Published: American Society for Microbiology 2019-03-01
Series:mBio
Subjects:
Aspergillus fumigatus
GPCR
MAP kinases
melanin
Online Access:https://doi.org/10.1128/mBio.00215-19

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