Viral Myocarditis: Clinical and Paraclinical Diagnosis
Myocarditis is an inflammatory disease of the myocardium, that can be produced by a multitude of infectious or noninfectious agents. The incidence rate of the disease is between 10 to 22 per 100,000 individuals. Among the infectious causes, viruses are considered to be the most frequent pathogens. R...
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doaj-1772d10b22d146678d7df6c6d9dddd4f2021-06-02T10:49:51ZengMedia Med PublicisModern Medicine1223-04722360-24732020-06-012728386https://doi.org/10.31689/rmm.2020.27.2.83Viral Myocarditis: Clinical and Paraclinical DiagnosisGabriela CEOBANU0Gina GHEORGHE1Ovidiu BRATU2Nicolae BACALBASA3Mihaela C. OLARIU4Tiberiu P. Neagu5Camelia DIACONU6Clinical Emergency Hospital, Bucharest, RomaniaClinical Emergency Hospital, Bucharest, RomaniaUniversity Emergency Central Military Hospital, Academy of Romanian Scientists, Bucharest, Romania„Ion Cantacuzino” Clinical Hospital, Bucharest, Romania„Matei Bals” National Institute of Infectious Diseases, Bucharest, RomaniaClinical Emergency Hospital, Bucharest, RomaniaClinical Emergency Hospital, Bucharest, RomaniaMyocarditis is an inflammatory disease of the myocardium, that can be produced by a multitude of infectious or noninfectious agents. The incidence rate of the disease is between 10 to 22 per 100,000 individuals. Among the infectious causes, viruses are considered to be the most frequent pathogens. Regarding the clinical presentation, viral myocarditis may have a wide variety of manifestations, ranging from asymptomatic disease to chest pain, myalgia, fatigue, heart failure, arrhythmias and, in some cases, sudden death. A definitive diagnosis of viral myocarditis involves histological evidence for myocarditis associated with positive viral polymerase chain reaction (PCR). Endomyocardial biopsy represents the gold standard for diagnosis; in the absence of histological, immunologic and immunohistochemical criteria, a definitive diagnosis cannot be established.https://medicinamoderna.ro/wp-content/uploads/2020/06/RMM_art-3.pdfviral myocarditisendomyocardial biopsyhistology |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Gabriela CEOBANU Gina GHEORGHE Ovidiu BRATU Nicolae BACALBASA Mihaela C. OLARIU Tiberiu P. Neagu Camelia DIACONU |
spellingShingle |
Gabriela CEOBANU Gina GHEORGHE Ovidiu BRATU Nicolae BACALBASA Mihaela C. OLARIU Tiberiu P. Neagu Camelia DIACONU Viral Myocarditis: Clinical and Paraclinical Diagnosis Modern Medicine viral myocarditis endomyocardial biopsy histology |
author_facet |
Gabriela CEOBANU Gina GHEORGHE Ovidiu BRATU Nicolae BACALBASA Mihaela C. OLARIU Tiberiu P. Neagu Camelia DIACONU |
author_sort |
Gabriela CEOBANU |
title |
Viral Myocarditis: Clinical and Paraclinical Diagnosis |
title_short |
Viral Myocarditis: Clinical and Paraclinical Diagnosis |
title_full |
Viral Myocarditis: Clinical and Paraclinical Diagnosis |
title_fullStr |
Viral Myocarditis: Clinical and Paraclinical Diagnosis |
title_full_unstemmed |
Viral Myocarditis: Clinical and Paraclinical Diagnosis |
title_sort |
viral myocarditis: clinical and paraclinical diagnosis |
publisher |
Media Med Publicis |
series |
Modern Medicine |
issn |
1223-0472 2360-2473 |
publishDate |
2020-06-01 |
description |
Myocarditis is an inflammatory disease of the myocardium, that can be produced by a multitude of infectious or noninfectious agents. The incidence rate of the disease is between 10 to 22 per 100,000 individuals. Among the infectious causes, viruses are considered to be the most frequent pathogens. Regarding the clinical presentation, viral myocarditis may have a wide variety of manifestations, ranging from asymptomatic disease to chest pain, myalgia, fatigue, heart failure, arrhythmias and, in some cases, sudden death. A definitive diagnosis of viral myocarditis involves histological evidence for myocarditis associated with positive viral polymerase chain reaction (PCR).
Endomyocardial biopsy represents the gold standard for diagnosis; in the absence of histological, immunologic and immunohistochemical criteria, a definitive diagnosis cannot be established. |
topic |
viral myocarditis endomyocardial biopsy histology |
url |
https://medicinamoderna.ro/wp-content/uploads/2020/06/RMM_art-3.pdf |
work_keys_str_mv |
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