Several Plasmodium vivax relapses after correct primaquine treatment in a patient with impaired cytochrome P450 2D6 function

Several Plasmodium vivax relapses after correct primaquine treatment in a patient with impaired cytochrome P450 2D6 function

Abstract Background Plasmodium vivax malaria is characterized by the presence of dormant liver-stage parasites, called hypnozoites, which can cause malaria relapses after an initial attack. Primaquine, which targets liver hypnozoites, must be used in combination with a schizonticidal agent to get th...

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Bibliographic Details
Main Authors: Alexandra Martin Ramírez, Carlos Lombardia González, Tamara Soler Maniega, Ángela Gutierrez Liarte, Diego Domingo García, Marta Lanza Suárez, María Josefa Bernal Fernández, José Miguel Rubio
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Malaria Journal
Subjects:
Plasmodium vivax
Malaria
Relapse
CYP2D6
Primaquine
Online Access:http://link.springer.com/article/10.1186/s12936-020-03326-1

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