Lipids and leptin level in natives of Kyrgyzstan
Objectives: A possible link between obesity and impaired lipid metabolism is leptin, the 167-amino acid protein, secreted by adipocytes. The content of leptin in the body is closely associated with body mass index (BMI). Data obtained from studies on the association of leptin with dyslipidemia are...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
KARE Publishing
2014-04-01
|
Series: | Türk Kardiyoloji Derneği Arşivi |
Subjects: | |
Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-39586 |
id |
doaj-178c9e11debb44ed8cea1cb0982f1407 |
---|---|
record_format |
Article |
spelling |
doaj-178c9e11debb44ed8cea1cb0982f14072021-01-19T07:06:36ZengKARE PublishingTürk Kardiyoloji Derneği Arşivi1016-51692014-04-0142325325810.5543/tkda.2014.39586TKDA-39586Lipids and leptin level in natives of KyrgyzstanErkin Mirrakhimov0Alina Kerimkulova1Olga Lunegova2Aibek Mirrakhimov3Nazira Alibaeva4Malik Nabiev5Department of Internal Medicine, Kyrgyz State Medical Academy, Bishkek, KyrgyzstanDepartment of Internal Medicine, Kyrgyz State Medical Academy, Bishkek, KyrgyzstanNational Center of Cardiology and Internal Disease, Bishkek, KyrgyzstanDepartment of Internal Medicine, Kyrgyz State Medical Academy, Bishkek, KyrgyzstanKyrgyz-Russian (Slavic) Univeristy, Bishkek, KyrgyzstanDepartment of Internal Medicine, Kyrgyz State Medical Academy, Bishkek, KyrgyzstanObjectives: A possible link between obesity and impaired lipid metabolism is leptin, the 167-amino acid protein, secreted by adipocytes. The content of leptin in the body is closely associated with body mass index (BMI). Data obtained from studies on the association of leptin with dyslipidemia are contradictory. The level of leptin has not been studied in the ethnic Kyrgyz population previously. The purpose of this study was to investigate the relationship between leptin and lipid parameters in a group of ethnic Kyrgyz. Study design: The study included 322 ethnic Kyrgyz (145 males, 177 females) aged ≥30 years, living in Kyrgyzstan. Measurement of anthropometric parameters (height, weight, waist circumference [WC], hip circumference [HC]) and blood pressure (BP) was done. Laboratory tests included blood glucose (fasting) in plasma, lipid profile (total cholesterol [TC], triglycerides [TG], high-density lipoprotein [HDL] cholesterol, low-density lipoprotein [LDL] cholesterol), and serum leptin. Results: Leptin was positively correlated with BMI, WC and TG in both sexes and with TC in males. Conclusion: Leptin is associated with BMI, WC and TG in both sexes of Kyrgyz and with TC in Kyrgyz males.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-39586lipidsleptinbody mass indexwaist circumference |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Erkin Mirrakhimov Alina Kerimkulova Olga Lunegova Aibek Mirrakhimov Nazira Alibaeva Malik Nabiev |
spellingShingle |
Erkin Mirrakhimov Alina Kerimkulova Olga Lunegova Aibek Mirrakhimov Nazira Alibaeva Malik Nabiev Lipids and leptin level in natives of Kyrgyzstan Türk Kardiyoloji Derneği Arşivi lipids leptin body mass index waist circumference |
author_facet |
Erkin Mirrakhimov Alina Kerimkulova Olga Lunegova Aibek Mirrakhimov Nazira Alibaeva Malik Nabiev |
author_sort |
Erkin Mirrakhimov |
title |
Lipids and leptin level in natives of Kyrgyzstan |
title_short |
Lipids and leptin level in natives of Kyrgyzstan |
title_full |
Lipids and leptin level in natives of Kyrgyzstan |
title_fullStr |
Lipids and leptin level in natives of Kyrgyzstan |
title_full_unstemmed |
Lipids and leptin level in natives of Kyrgyzstan |
title_sort |
lipids and leptin level in natives of kyrgyzstan |
publisher |
KARE Publishing |
series |
Türk Kardiyoloji Derneği Arşivi |
issn |
1016-5169 |
publishDate |
2014-04-01 |
description |
Objectives: A possible link between obesity and impaired lipid metabolism is leptin, the 167-amino acid protein, secreted by adipocytes. The content of leptin in the body is closely associated with body mass index (BMI). Data obtained from studies on the association of leptin with dyslipidemia are contradictory. The level of leptin has not been studied in the ethnic Kyrgyz population previously. The purpose of this study was to investigate the relationship between leptin and lipid parameters in a group of ethnic Kyrgyz.
Study design: The study included 322 ethnic Kyrgyz (145 males, 177 females) aged ≥30 years, living in Kyrgyzstan. Measurement of anthropometric parameters (height, weight, waist circumference [WC], hip circumference [HC]) and blood pressure (BP) was done. Laboratory tests included blood glucose (fasting) in plasma, lipid profile (total cholesterol [TC], triglycerides [TG], high-density lipoprotein [HDL] cholesterol, low-density lipoprotein [LDL] cholesterol), and serum leptin.
Results: Leptin was positively correlated with BMI, WC and TG in both sexes and with TC in males.
Conclusion: Leptin is associated with BMI, WC and TG in both sexes of Kyrgyz and with TC in Kyrgyz males. |
topic |
lipids leptin body mass index waist circumference |
url |
https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-39586 |
work_keys_str_mv |
AT erkinmirrakhimov lipidsandleptinlevelinnativesofkyrgyzstan AT alinakerimkulova lipidsandleptinlevelinnativesofkyrgyzstan AT olgalunegova lipidsandleptinlevelinnativesofkyrgyzstan AT aibekmirrakhimov lipidsandleptinlevelinnativesofkyrgyzstan AT naziraalibaeva lipidsandleptinlevelinnativesofkyrgyzstan AT maliknabiev lipidsandleptinlevelinnativesofkyrgyzstan |
_version_ |
1724332460269895680 |