Human microcephaly protein RTTN interacts with STIL and is required to build full-length centrioles
Mutations in many centriolar protein-encoding genes cause primary microcephaly. Here the authors show that human microcephaly protein RTTN directly interacts with STIL and acts downstream of STIL-mediated centriole assembly, contributing to building full-length centrioles
Main Authors: | Hsin-Yi Chen, Chien-Ting Wu, Chieh-Ju C. Tang, Yi-Nan Lin, Won-Jing Wang, Tang K. Tang |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-08-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-017-00305-0 |
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