Association between obesity and lipid profile in children 10--12 years of age
Background Worldwide prevalence of obesity in children has been increasing. Together with dyslipidemia and hypertension, obesity is associated with higher risk of cardiovascular morbidity later in life. Objective The aim of this study was to assess association between obesity and occurrence of dysli...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Indonesian Pediatric Society Publishing House
2016-09-01
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Series: | Paediatrica Indonesiana |
Subjects: | |
Online Access: | https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/592 |
Summary: | Background Worldwide prevalence of obesity in children has
been increasing. Together with dyslipidemia and hypertension,
obesity is associated with higher risk of cardiovascular morbidity
later in life.
Objective The aim of this study was to assess association
between obesity and occurrence of dyslipidemia in 10-12 years
old children.
Methods We performed a cross sectional study on 53 obese and
53 non-obese children matched for age and gender in Yogyakarta.
Obesity was defined as body mass index (BMI) at or above the
95th percentile of the CDC 2000 reference. The levels of total
cholesterol, LDL-cholesterol, HDL-cholesterol and triglyceride
were measured. Dyslipidemia was defined as increased level of
total cholesterol, LDL-cholesterol, triglyceride and decreased
level of HDL-cholesterol.
Results Obese children had higher risk of increased level of
triglyseride, i.e. RR 2.6 (95% CI 1.6 to 4.4), P<O.OOl and
decreased level ofHDL-cholesterol, i.e. RR 17.8 (95%CI 14.0 to
20.1), P=0.003. Overall, relative risk for dyslipidemia in obese
children was 5.2 (95%CI 4.2 to 5.9), P=0.002, higher than in
non-obese children.
Conclusion Compared to non-obese children, obese children have
higher risk of dyslipidemia, particularly hypertriglyceridemia and
hypo-HDL. |
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ISSN: | 0030-9311 2338-476X |