Deficiency of G9a Inhibits Cell Proliferation and Activates Autophagy via Transcriptionally Regulating c-Myc Expression in Glioblastoma
Glioblastoma is an aggressive and difficult to treat cancer. Recent data have emerged implicating that histone modification level may play a crucial role in glioma genesis. The histone lysine methyltransferase G9a is mainly responsible for the mono- and di-methylation of histone H3 lysine 9 (H3K9),...
Main Authors: | Xiao Xue Ke, Rui Zhang, Xi Zhong, Lei Zhang, Hongjuan Cui |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-11-01
|
Series: | Frontiers in Cell and Developmental Biology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fcell.2020.593964/full |
Similar Items
-
TRIM28 activates autophagy and promotes cell proliferation in glioblastoma
by: Peng Y, et al.
Published: (2019-01-01) -
Polydatin Inhibits Cell Viability, Migration, and Invasion Through Suppressing the c-Myc Expression in Human Cervical Cancer
by: Longchang Bai, et al.
Published: (2021-04-01) -
PTPN18 promotes colorectal cancer progression by regulating the c-MYC-CDK4 axis
by: Chao Li, et al.
Published: (2021-11-01) -
The Emerging Roles of RNA Modifications in Glioblastoma
by: Zhen Dong, et al.
Published: (2020-03-01) -
Inhibition of H3K9 methyltransferase G9a repressed cell proliferation and induced autophagy in neuroblastoma cells.
by: Xiao-Xue Ke, et al.
Published: (2014-01-01)