Plant Secondary Metabolite-Derived Polymers: A Potential Approach to Develop Antimicrobial Films
The persistent issue of bacterial and fungal colonization of artificial implantable materials and the decreasing efficacy of conventional systemic antibiotics used to treat implant-associated infections has led to the development of a wide range of antifouling and antibacterial strategies. This arti...
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doaj-17ca47914b1d48e89df6b828e5053f6d2020-11-24T23:26:24ZengMDPI AGPolymers2073-43602018-05-0110551510.3390/polym10050515polym10050515Plant Secondary Metabolite-Derived Polymers: A Potential Approach to Develop Antimicrobial FilmsAhmed Al-Jumaili0Avishek Kumar1Kateryna Bazaka2Mohan V. Jacob3Electronics Materials Lab, College of Science and Engineering, James Cook University, Townsville, QLD 4811, AustraliaElectronics Materials Lab, College of Science and Engineering, James Cook University, Townsville, QLD 4811, AustraliaElectronics Materials Lab, College of Science and Engineering, James Cook University, Townsville, QLD 4811, AustraliaElectronics Materials Lab, College of Science and Engineering, James Cook University, Townsville, QLD 4811, AustraliaThe persistent issue of bacterial and fungal colonization of artificial implantable materials and the decreasing efficacy of conventional systemic antibiotics used to treat implant-associated infections has led to the development of a wide range of antifouling and antibacterial strategies. This article reviews one such strategy where inherently biologically active renewable resources, i.e., plant secondary metabolites (PSMs) and their naturally occurring combinations (i.e., essential oils) are used for surface functionalization and synthesis of polymer thin films. With a distinct mode of antibacterial activity, broad spectrum of action, and diversity of available chemistries, plant secondary metabolites present an attractive alternative to conventional antibiotics. However, their conversion from liquid to solid phase without a significant loss of activity is not trivial. Using selected examples, this article shows how plasma techniques provide a sufficiently flexible and chemically reactive environment to enable the synthesis of biologically-active polymer coatings from volatile renewable resources.http://www.mdpi.com/2073-4360/10/5/515volatile renewable resourcesmicrobial infectionplant secondary metabolitesantimicrobial essential oilsbiologically-active polymersplasma-assisted technique |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Ahmed Al-Jumaili Avishek Kumar Kateryna Bazaka Mohan V. Jacob |
spellingShingle |
Ahmed Al-Jumaili Avishek Kumar Kateryna Bazaka Mohan V. Jacob Plant Secondary Metabolite-Derived Polymers: A Potential Approach to Develop Antimicrobial Films Polymers volatile renewable resources microbial infection plant secondary metabolites antimicrobial essential oils biologically-active polymers plasma-assisted technique |
author_facet |
Ahmed Al-Jumaili Avishek Kumar Kateryna Bazaka Mohan V. Jacob |
author_sort |
Ahmed Al-Jumaili |
title |
Plant Secondary Metabolite-Derived Polymers: A Potential Approach to Develop Antimicrobial Films |
title_short |
Plant Secondary Metabolite-Derived Polymers: A Potential Approach to Develop Antimicrobial Films |
title_full |
Plant Secondary Metabolite-Derived Polymers: A Potential Approach to Develop Antimicrobial Films |
title_fullStr |
Plant Secondary Metabolite-Derived Polymers: A Potential Approach to Develop Antimicrobial Films |
title_full_unstemmed |
Plant Secondary Metabolite-Derived Polymers: A Potential Approach to Develop Antimicrobial Films |
title_sort |
plant secondary metabolite-derived polymers: a potential approach to develop antimicrobial films |
publisher |
MDPI AG |
series |
Polymers |
issn |
2073-4360 |
publishDate |
2018-05-01 |
description |
The persistent issue of bacterial and fungal colonization of artificial implantable materials and the decreasing efficacy of conventional systemic antibiotics used to treat implant-associated infections has led to the development of a wide range of antifouling and antibacterial strategies. This article reviews one such strategy where inherently biologically active renewable resources, i.e., plant secondary metabolites (PSMs) and their naturally occurring combinations (i.e., essential oils) are used for surface functionalization and synthesis of polymer thin films. With a distinct mode of antibacterial activity, broad spectrum of action, and diversity of available chemistries, plant secondary metabolites present an attractive alternative to conventional antibiotics. However, their conversion from liquid to solid phase without a significant loss of activity is not trivial. Using selected examples, this article shows how plasma techniques provide a sufficiently flexible and chemically reactive environment to enable the synthesis of biologically-active polymer coatings from volatile renewable resources. |
topic |
volatile renewable resources microbial infection plant secondary metabolites antimicrobial essential oils biologically-active polymers plasma-assisted technique |
url |
http://www.mdpi.com/2073-4360/10/5/515 |
work_keys_str_mv |
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