The location and trafficking routes of the neuronal retromer and its role in amyloid precursor protein transport

The location and trafficking routes of the neuronal retromer and its role in amyloid precursor protein transport

The retromer complex plays an important role in intracellular transport, is highly expressed in the hippocampus, and has been implicated in the trafficking of the amyloid precursor protein (APP). Nevertheless, the trafficking routes of the neuronal retromer and the role it plays in APP transport in...

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Bibliographic Details
Main Authors: Akhil Bhalla, Christopher P. Vetanovetz, Etienne Morel, Zeina Chamoun, Gilbert Di Paolo, Scott A. Small
Format: Article
Language:English
Published: Elsevier 2012-07-01
Series:Neurobiology of Disease
Subjects:
Alzheimer's disease
Retromer
Amyloid precursor protein
Abeta
Trafficking
Neurobiology
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996112001192

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