Toward a better definition of hematopoietic progenitors suitable for B cell differentiation.

The success of inducing human pluripotent stem cells (hIPSC) offers new opportunities for cell-based therapy. Since B cells exert roles as effector and as regulator of immune responses in different clinical settings, we were interested in generating B cells from hIPSC. We differentiated human embryo...

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Bibliographic Details
Main Authors: Florian Dubois, Anne Gaignerie, Léa Flippe, Jean-Marie Heslan, Laurent Tesson, Mélanie Chesneau, Fabienne Haspot, Sophie Conchon, Laurent David, Sophie Brouard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0243769