Design and fabrication of a vigorous “cavitation-on-a-chip” device with a multiple microchannel configuration
Abstract Hydrodynamic cavitation is one of the major phase change phenomena and occurs with a sudden decrease in the local static pressure within a fluid. With the emergence of microelectromechanical systems (MEMS), high-speed microfluidic devices have attracted considerable attention and been imple...
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doaj-1826963f7b2141049ed312d27ce3b6812021-06-06T11:18:18ZengNature Publishing GroupMicrosystems & Nanoengineering2055-74342021-06-017111310.1038/s41378-021-00270-1Design and fabrication of a vigorous “cavitation-on-a-chip” device with a multiple microchannel configurationFarzad Rokhsar Talabazar0Mohammad Jafarpour1Merve Zuvin2Hongjian Chen3Moein Talebian Gevari4Luis Guillermo Villanueva5Dmitry Grishenkov6Ali Koşar7Morteza Ghorbani8Faculty of Engineering and Natural Science, Sabanci UniversityFaculty of Engineering and Natural Science, Sabanci UniversityFaculty of Engineering and Natural Science, Sabanci UniversityDepartment of Biomedical Engineering and Health Systems, KTH Royal Institute of TechnologyDivision of Solid State Electronics, Department of Electrical Engineering, The Ångström Laboratory, Uppsala UniversityAdvanced NEMS Laboratory, École Polytechnique Fédérale de Lausanne (EPFL)Department of Biomedical Engineering and Health Systems, KTH Royal Institute of TechnologyFaculty of Engineering and Natural Science, Sabanci UniversitySabanci University Nanotechnology Research and Application CenterAbstract Hydrodynamic cavitation is one of the major phase change phenomena and occurs with a sudden decrease in the local static pressure within a fluid. With the emergence of microelectromechanical systems (MEMS), high-speed microfluidic devices have attracted considerable attention and been implemented in many fields, including cavitation applications. In this study, a new generation of ‘cavitation-on-a-chip’ devices with eight parallel structured microchannels is proposed. This new device is designed with the motivation of decreasing the upstream pressure (input energy) required for facile hydrodynamic cavitation inception. Water and a poly(vinyl alcohol) (PVA) microbubble (MB) suspension are used as the working fluids. The results show that the cavitation inception upstream pressure can be reduced with the proposed device in comparison with previous studies with a single flow restrictive element. Furthermore, using PVA MBs further results in a reduction in the upstream pressure required for cavitation inception. In this new device, different cavitating flow patterns with various intensities can be observed at a constant cavitation number and fixed upstream pressure within the same device. Moreover, cavitating flows intensify faster in the proposed device for both water and the water–PVA MB suspension in comparison to previous studies. Due to these features, this next-generation ‘cavitation-on-a-chip’ device has a high potential for implementation in applications involving microfluidic/organ-on-a-chip devices, such as integrated drug release and tissue engineering.https://doi.org/10.1038/s41378-021-00270-1 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Farzad Rokhsar Talabazar Mohammad Jafarpour Merve Zuvin Hongjian Chen Moein Talebian Gevari Luis Guillermo Villanueva Dmitry Grishenkov Ali Koşar Morteza Ghorbani |
spellingShingle |
Farzad Rokhsar Talabazar Mohammad Jafarpour Merve Zuvin Hongjian Chen Moein Talebian Gevari Luis Guillermo Villanueva Dmitry Grishenkov Ali Koşar Morteza Ghorbani Design and fabrication of a vigorous “cavitation-on-a-chip” device with a multiple microchannel configuration Microsystems & Nanoengineering |
author_facet |
Farzad Rokhsar Talabazar Mohammad Jafarpour Merve Zuvin Hongjian Chen Moein Talebian Gevari Luis Guillermo Villanueva Dmitry Grishenkov Ali Koşar Morteza Ghorbani |
author_sort |
Farzad Rokhsar Talabazar |
title |
Design and fabrication of a vigorous “cavitation-on-a-chip” device with a multiple microchannel configuration |
title_short |
Design and fabrication of a vigorous “cavitation-on-a-chip” device with a multiple microchannel configuration |
title_full |
Design and fabrication of a vigorous “cavitation-on-a-chip” device with a multiple microchannel configuration |
title_fullStr |
Design and fabrication of a vigorous “cavitation-on-a-chip” device with a multiple microchannel configuration |
title_full_unstemmed |
Design and fabrication of a vigorous “cavitation-on-a-chip” device with a multiple microchannel configuration |
title_sort |
design and fabrication of a vigorous “cavitation-on-a-chip” device with a multiple microchannel configuration |
publisher |
Nature Publishing Group |
series |
Microsystems & Nanoengineering |
issn |
2055-7434 |
publishDate |
2021-06-01 |
description |
Abstract Hydrodynamic cavitation is one of the major phase change phenomena and occurs with a sudden decrease in the local static pressure within a fluid. With the emergence of microelectromechanical systems (MEMS), high-speed microfluidic devices have attracted considerable attention and been implemented in many fields, including cavitation applications. In this study, a new generation of ‘cavitation-on-a-chip’ devices with eight parallel structured microchannels is proposed. This new device is designed with the motivation of decreasing the upstream pressure (input energy) required for facile hydrodynamic cavitation inception. Water and a poly(vinyl alcohol) (PVA) microbubble (MB) suspension are used as the working fluids. The results show that the cavitation inception upstream pressure can be reduced with the proposed device in comparison with previous studies with a single flow restrictive element. Furthermore, using PVA MBs further results in a reduction in the upstream pressure required for cavitation inception. In this new device, different cavitating flow patterns with various intensities can be observed at a constant cavitation number and fixed upstream pressure within the same device. Moreover, cavitating flows intensify faster in the proposed device for both water and the water–PVA MB suspension in comparison to previous studies. Due to these features, this next-generation ‘cavitation-on-a-chip’ device has a high potential for implementation in applications involving microfluidic/organ-on-a-chip devices, such as integrated drug release and tissue engineering. |
url |
https://doi.org/10.1038/s41378-021-00270-1 |
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