Magnesium uptake by connecting fluid-phase endocytosis to an intracellular inorganic cation filter
Metal bioavailability is frequently limited by sequestering agents which makes them inaccessible to cells. Here the authors show that cells can increase Mg2+ uptake via fluid phase endocytosis and accumulate this metal in their vacuole loaded with polyphosphate, and later can be exported to the cyto...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-12-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-017-01930-5 |
id |
doaj-182bfaf9f5b64f8ab6a9e7760493db68 |
---|---|
record_format |
Article |
spelling |
doaj-182bfaf9f5b64f8ab6a9e7760493db682021-05-11T07:04:01ZengNature Publishing GroupNature Communications2041-17232017-12-018111210.1038/s41467-017-01930-5Magnesium uptake by connecting fluid-phase endocytosis to an intracellular inorganic cation filterSandra H. Klompmaker0Kid Kohl1Nicolas Fasel2Andreas Mayer3Department of Biochemistry, University of LausanneDepartment of Biochemistry, University of LausanneDepartment of Biochemistry, University of LausanneDepartment of Biochemistry, University of LausanneMetal bioavailability is frequently limited by sequestering agents which makes them inaccessible to cells. Here the authors show that cells can increase Mg2+ uptake via fluid phase endocytosis and accumulate this metal in their vacuole loaded with polyphosphate, and later can be exported to the cytosol.https://doi.org/10.1038/s41467-017-01930-5 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Sandra H. Klompmaker Kid Kohl Nicolas Fasel Andreas Mayer |
spellingShingle |
Sandra H. Klompmaker Kid Kohl Nicolas Fasel Andreas Mayer Magnesium uptake by connecting fluid-phase endocytosis to an intracellular inorganic cation filter Nature Communications |
author_facet |
Sandra H. Klompmaker Kid Kohl Nicolas Fasel Andreas Mayer |
author_sort |
Sandra H. Klompmaker |
title |
Magnesium uptake by connecting fluid-phase endocytosis to an intracellular inorganic cation filter |
title_short |
Magnesium uptake by connecting fluid-phase endocytosis to an intracellular inorganic cation filter |
title_full |
Magnesium uptake by connecting fluid-phase endocytosis to an intracellular inorganic cation filter |
title_fullStr |
Magnesium uptake by connecting fluid-phase endocytosis to an intracellular inorganic cation filter |
title_full_unstemmed |
Magnesium uptake by connecting fluid-phase endocytosis to an intracellular inorganic cation filter |
title_sort |
magnesium uptake by connecting fluid-phase endocytosis to an intracellular inorganic cation filter |
publisher |
Nature Publishing Group |
series |
Nature Communications |
issn |
2041-1723 |
publishDate |
2017-12-01 |
description |
Metal bioavailability is frequently limited by sequestering agents which makes them inaccessible to cells. Here the authors show that cells can increase Mg2+ uptake via fluid phase endocytosis and accumulate this metal in their vacuole loaded with polyphosphate, and later can be exported to the cytosol. |
url |
https://doi.org/10.1038/s41467-017-01930-5 |
work_keys_str_mv |
AT sandrahklompmaker magnesiumuptakebyconnectingfluidphaseendocytosistoanintracellularinorganiccationfilter AT kidkohl magnesiumuptakebyconnectingfluidphaseendocytosistoanintracellularinorganiccationfilter AT nicolasfasel magnesiumuptakebyconnectingfluidphaseendocytosistoanintracellularinorganiccationfilter AT andreasmayer magnesiumuptakebyconnectingfluidphaseendocytosistoanintracellularinorganiccationfilter |
_version_ |
1721452767805964288 |