Aspectos genéticos do transtorno obsessivo-compulsivo
Since the first descriptions of obsessive-compulsive disorder (OCD), genetic factors have been implicated in the etiology of the illness. Twin studies show a high concordance rate for monozygotic twins. Family studies found a higher risk for OCD among relatives of OCD patients. Segregation analysis...
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Format: | Article |
Language: | English |
Published: |
Associação Brasileira de Psiquiatria (ABP)
2001-01-01
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Series: | Brazilian Journal of Psychiatry |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462001000600012 |
Summary: | Since the first descriptions of obsessive-compulsive disorder (OCD), genetic factors have been implicated in the etiology of the illness. Twin studies show a high concordance rate for monozygotic twins. Family studies found a higher risk for OCD among relatives of OCD patients. Segregation analysis studies suggest the possible role of a major effect gene in the etiology of OCD. Association studies using molecular techniques have been conducted to try to find a specific gene or polymorphism involved in OCD. This review outlines the evidence gathered to date, including the recent findings in the molecular genetics analysis. |
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ISSN: | 1516-4446 |