Assessment of an in vitro model of human cells to evaluate the toxic and irritating potential of chemical compounds

Assessment of an in vitro model of human cells to evaluate the toxic and irritating potential of chemical compounds

We attempted to induce differentation in unidifferentiated NCTC2544 human keratinocyte line, by exposure to ZnSO<sub>4</sub> and CaCl<sub>2</sub>. Analysis of specific markers, transglutaminase I, involucrin and loricrin, show that basal NCTC2544 (BL) reached spinous- (SL) an...

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Bibliographic Details
Main Authors: M. Catalano, C. Scanarotti, R. Sanguineti, S. Penco, P. Romano, A. Cadoni, M.A. Pronzato, A.M. Bassi
Format: Article
Language:English
Published: PAGEPress Publications 2011-01-01
Series:Journal of Biological Research
Subjects:
differentation, kerationcytes, in vitro, irritation
Online Access:http://www.pagepressjournals.org/index.php/jbr/article/view/4481

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