Clinical evaluation of the effectiveness of fusion‐induced asymmetric transcription assay‐based reverse transcription droplet digital PCR for ALK detection in formalin‐fixed paraffin‐embedded samples from lung cancer
Background Accurate detection of anaplastic lymphoma kinase (ALK) rearrangement is the prerequisite for anti‐ALK therapy for the patient with non‐small cell lung cancer (NSCLC). Fusion‐induced asymmetric transcription assay (FIATA)‐based reverse transcription droplet digital PCR (RT‐ddPCR) was devel...
Main Authors: | Yuanyuan Liu, Shafei Wu, Xiaohua Shi, Linping Lu, Lingxiang Zhu, Yong Guo, Li Zhang, Xuan Zeng |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2020-08-01
|
Series: | Thoracic Cancer |
Subjects: | |
Online Access: | https://doi.org/10.1111/1759-7714.13535 |
Similar Items
-
Changing ALK-TKI-Resistance Mechanisms in Rebiopsies of <i>ALK</i>-Rearranged NSCLC: <i>ALK</i>- and <i>BRAF</i>-Mutations Followed by Epithelial-Mesenchymal Transition
by: Edyta M. Urbanska, et al.
Published: (2020-04-01) -
The Transcriptional Roles of ALK Fusion Proteins in Tumorigenesis
by: Stephen P. Ducray, et al.
Published: (2019-07-01) -
ALK‐rearranged squamous cell carcinoma of the lung
by: Qiyi Meng, et al.
Published: (2021-04-01) -
Highly sensitive detection of ALK resistance mutations in plasma using droplet digital PCR
by: Ryohei Yoshida, et al.
Published: (2018-11-01) -
STK3-ALK, a Novel ALK Rearrangement in Non-Small Cell Lung Cancer With Sensitivity to Tyrosine Kinase Inhibitors: A Case Report
by: Chunlai Feng, et al.
Published: (2021-08-01)