Nonradiographic axial spondyloarthritis: clinical and therapeutic relevance
Abstract Current classification criteria for axial spondyloarthritis (axSpA) provide for the inclusion of patients with a wide range of presentations and manifestations. While not considered a formal subclassification, patients are often divided into radiographic or nonradiographic axSpA based on th...
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doaj-18abc1f6d1cc417897e89f423ee2e1a82020-11-25T00:46:25ZengBMCArthritis Research & Therapy1478-63622017-12-011911910.1186/s13075-017-1493-8Nonradiographic axial spondyloarthritis: clinical and therapeutic relevanceNilasha Ghosh0Eric M. Ruderman1Northwestern University Feinberg School of MedicineNorthwestern University Feinberg School of MedicineAbstract Current classification criteria for axial spondyloarthritis (axSpA) provide for the inclusion of patients with a wide range of presentations and manifestations. While not considered a formal subclassification, patients are often divided into radiographic or nonradiographic axSpA based on the presence or absence of radiographic sacroiliitis. This review will focus on nonradiographic axSpA and will discuss clinical manifestations of disease that distinguish, or in many cases do not distinguish, this entity from other individuals with axSpA. This review will also cover treatment paradigms for nonradiographic axSpA, particularly the use of biologic therapies, where current data suggest that nonradiographic disease should be managed largely the same as radiographic disease, or classical ankylosing spondylitis.http://link.springer.com/article/10.1186/s13075-017-1493-8Axial spondyloarthritisNonradiographic axial spondyloarthritisDisease classificationTherapyBiologic therapy |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Nilasha Ghosh Eric M. Ruderman |
spellingShingle |
Nilasha Ghosh Eric M. Ruderman Nonradiographic axial spondyloarthritis: clinical and therapeutic relevance Arthritis Research & Therapy Axial spondyloarthritis Nonradiographic axial spondyloarthritis Disease classification Therapy Biologic therapy |
author_facet |
Nilasha Ghosh Eric M. Ruderman |
author_sort |
Nilasha Ghosh |
title |
Nonradiographic axial spondyloarthritis: clinical and therapeutic relevance |
title_short |
Nonradiographic axial spondyloarthritis: clinical and therapeutic relevance |
title_full |
Nonradiographic axial spondyloarthritis: clinical and therapeutic relevance |
title_fullStr |
Nonradiographic axial spondyloarthritis: clinical and therapeutic relevance |
title_full_unstemmed |
Nonradiographic axial spondyloarthritis: clinical and therapeutic relevance |
title_sort |
nonradiographic axial spondyloarthritis: clinical and therapeutic relevance |
publisher |
BMC |
series |
Arthritis Research & Therapy |
issn |
1478-6362 |
publishDate |
2017-12-01 |
description |
Abstract Current classification criteria for axial spondyloarthritis (axSpA) provide for the inclusion of patients with a wide range of presentations and manifestations. While not considered a formal subclassification, patients are often divided into radiographic or nonradiographic axSpA based on the presence or absence of radiographic sacroiliitis. This review will focus on nonradiographic axSpA and will discuss clinical manifestations of disease that distinguish, or in many cases do not distinguish, this entity from other individuals with axSpA. This review will also cover treatment paradigms for nonradiographic axSpA, particularly the use of biologic therapies, where current data suggest that nonradiographic disease should be managed largely the same as radiographic disease, or classical ankylosing spondylitis. |
topic |
Axial spondyloarthritis Nonradiographic axial spondyloarthritis Disease classification Therapy Biologic therapy |
url |
http://link.springer.com/article/10.1186/s13075-017-1493-8 |
work_keys_str_mv |
AT nilashaghosh nonradiographicaxialspondyloarthritisclinicalandtherapeuticrelevance AT ericmruderman nonradiographicaxialspondyloarthritisclinicalandtherapeuticrelevance |
_version_ |
1725265614475362304 |