ORAI1 Ca2+ Channel as a Therapeutic Target in Pathological Vascular Remodelling
In the adult, vascular smooth muscle cells (VSMC) are normally physiologically quiescent, arranged circumferentially in one or more layers within blood vessel walls. Remodelling of native VSMC to a proliferative state for vascular development, adaptation or repair is driven by platelet-derived growt...
Main Authors: | Heba Shawer, Katherine Norman, Chew W. Cheng, Richard Foster, David J. Beech, Marc A. Bailey |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-04-01
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Series: | Frontiers in Cell and Developmental Biology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fcell.2021.653812/full |
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